Publication: Protective Effect of Centranthus longiflorus subsp, longiflorus in Glutamate-Induced Neurotoxicity
| dc.contributor.author | Buyukokuroglu M.E. | |
| dc.contributor.author | Gepdiremen A. | |
| dc.contributor.author | Halici Z. | |
| dc.contributor.author | Duzenli S. | |
| dc.contributor.author | Guyenalp Z. | |
| dc.contributor.author | Demirezer L.O. | |
| dc.date.accessioned | 2020-06-21T09:27:37Z | |
| dc.date.available | 2020-06-21T09:27:37Z | |
| dc.date.issued | 2010 | |
| dc.department | OMÜ | en_US |
| dc.department-temp | Buyukokuroglu, M.E., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Department of Pharmacology, Cetinkaya Kampusu, Afyon- izmir Yolu TR-03200, Afyon, Turkey -- Gepdiremen, A., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Afyon Kocatepe University, Faculty of Medicine, Samsun, Turkey -- Halici, Z., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Department of Pharmacology, Faculty of Medicine, Samsun, Turkey -- Duzenli, S., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Department of Pharmacology, Samsun, Turkey, Medical Biology and Genetic, Faculty of Medicine, Samsun Ondokuz Mayis University, Samsun, Turkey -- Guyenalp, Z., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University, Erzurum, Ankara, Turkey -- Demirezer, L.O., Department of Pharmacology, Faculty of Medicine, Afyon Kocatepe University, Afyon, Turkey, Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey -- | en_US |
| dc.description.abstract | In the present study, neuroprotective effect of the aquoeus extract of Centranthus longiflorus subsp. Iongiflorus in glutamate induced toxicity in rat pups cerebellar granular cell culture was investigated. The extract at doses of 50 ?g.ml-1, 100 ?.g.ml-1 250 ?g.ml-1, 500 ?g.ml-1 and 1000 ?g.ml-1 was applied to culture flasks. At all doses the extract significantly blocked glutamate - induced neurotoxicity, with the most effective dose being 500 ?g.ml-1. As a result, Centranthus longiflorus subsp. longiflorus protected the neurons against glutamate toxicity. | en_US |
| dc.identifier.endpage | 246 | en_US |
| dc.identifier.issn | 0019-6479 | |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.startpage | 244 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12712/4115 | |
| dc.identifier.volume | 87 | en_US |
| dc.language.iso | en | en_US |
| dc.relation.journal | Indian Veterinary Journal | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.title | Protective Effect of Centranthus longiflorus subsp, longiflorus in Glutamate-Induced Neurotoxicity | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication |