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Preventing Intraperitoneal Adhesions with Linezolid and Hyaluronic Acid/Carboxymethylcellulose: A Comparative Study in Cecal Abrasion Model

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dc.authorscopusid23666243700
dc.authorscopusid57210665350
dc.authorscopusid45560930200
dc.authorscopusid57214556307
dc.authorscopusid56496798000
dc.contributor.authorÇaǧlayan, K.
dc.contributor.authorGüngör, B.
dc.contributor.authorÇinar, H.
dc.contributor.authorErdog̀an, N.Y.
dc.contributor.authorKoca, B.
dc.date.accessioned2020-06-21T13:57:02Z
dc.date.available2020-06-21T13:57:02Z
dc.date.issued2014
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Çaǧlayan] Kasim, Department of Surgery, Bozok Üniversitesi, Yozgat, Turkey; [Güngör] Bülent, Department of Surgery, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Çinar] Hamza, Department of Surgery, Siirt State Hospital, Siirt, Siirt, Turkey; [Erdog̀an] Nilsen Yildirim,; [Koca] Bülent, Department of Surgery, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractBackground We aimed to compare the effectiveness of linezolid in preventing intraperitoneal adhesions with hyaluronic acid + carboxymethylcellulose (Seprafilm). Methods Thirty rats were divided randomly into 3 groups: Group I (control), untreated; Group II (Seprafilm); and Group III (linezolid). All rats were sacrificed on the 14th day after surgery. Macroscopic adhesion, inflammation, and fibrosis were evaluated. Results The multiple comparisons between groups showed a statistically significant difference for adhesion. There were statistically significant differences between Group I and II and I and III, but no statistically significant difference between Group II and III. The multiple comparisons between the groups showed a statistically significant difference for inflammation and fibrosis. For inflammation and fibrosis, there was a statistically significant difference between Group I and II and I and III, but no statistically significant difference between Group II and III. Conclusion The efficiency of linezolid in reducing the formation of intraperitoneal adhesions was statistically significant compared with the control group. © 2014 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.amjsurg.2012.05.038
dc.identifier.endpage111en_US
dc.identifier.issn0002-9610
dc.identifier.issn1879-1883
dc.identifier.issue1en_US
dc.identifier.pmid24814308
dc.identifier.scopus2-s2.0-84903182483
dc.identifier.scopusqualityQ1
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.1016/j.amjsurg.2012.05.038
dc.identifier.volume208en_US
dc.identifier.wosWOS:000338440700017
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherElsevier Inc. usjcs@elsevier.comen_US
dc.relation.ispartofAmerican Journal of Surgeryen_US
dc.relation.journalAmerican Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntraperitoneal Adhesionen_US
dc.subjectLinezoliden_US
dc.titlePreventing Intraperitoneal Adhesions with Linezolid and Hyaluronic Acid/Carboxymethylcellulose: A Comparative Study in Cecal Abrasion Modelen_US
dc.typeArticleen_US
dspace.entity.typePublication

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