Publication:
The Oncogenic Role of Holliday Junction Recognition Protein in Hepatocellular Carcinoma

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dc.authorscopusid56516442600
dc.authorscopusid57205685845
dc.authorscopusid59730057400
dc.contributor.authorYüce, M.
dc.contributor.authorAlbayrak, E.
dc.contributor.authorŞi̇şli̇, İ.
dc.date.accessioned2025-12-11T00:34:39Z
dc.date.issued2025
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Yüce] Melek, Stem Cell Research & Application Center, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Albayrak] Esra, Stem Cell Research & Application Center, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Şi̇şli̇] İlayda, Department of Medical Biology, Ondokuz Mayis University, Medical School, Samsun, Turkeyen_US
dc.description.abstractThe relationship between centromere dysfunction leading to numerical chromosomal changes and cancer is well-known. Holliday Junction Recognition Protein (HJURP) is a chaperone of the centromere-specific protein, Centromere Protein A (CENP-A), and is considered a critical factor in determining centromere identity. There are researches showing that CENP-A is overexpressed in many types of human cancer. However, the role and dynamics of HJURP in tumorigenesis have only recently been clarified. In this review, the connection between HJURP and liver cancer, as well as the role of HJURP in cancer development, has been summarized. © 2025 Ondokuz Mayis Universitesi. All rights reserved.en_US
dc.identifier.doi10.52142/omujecm.42.1.14
dc.identifier.endpage79en_US
dc.identifier.issn1309-4483
dc.identifier.issn1309-5129
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-105002217087
dc.identifier.scopusqualityQ4
dc.identifier.startpage69en_US
dc.identifier.urihttps://doi.org/10.52142/omujecm.42.1.14
dc.identifier.urihttps://hdl.handle.net/20.500.12712/37646
dc.identifier.volume42en_US
dc.language.isoenen_US
dc.publisherOndokuz Mayis Üniversitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicine (Turkey)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCENP-Aen_US
dc.subjectChaperoneen_US
dc.subjectHepatocellular Carcinomaen_US
dc.subjectHJURPen_US
dc.subjectLiver Canceren_US
dc.subjectPrognosisen_US
dc.titleThe Oncogenic Role of Holliday Junction Recognition Protein in Hepatocellular Carcinomaen_US
dc.typeArticleen_US
dspace.entity.typePublication

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