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Investigation of the correlation between mood disorder symptoms and disease activity and functional status in rheumatoid arthritis patients
(TÜBİTAK, 2021)To investigate the correlation between depressive-anxiety symptoms, mixed features, disease activity, and functional status in patients with rheumatoid arthritis (RA) in the light of the shared underlying etiology in both ... -
The inhibition of Src kinase suppresses the production of matrix metalloproteinases in from synovial fibroblasts and inhibits MAPK and STATs pathways
(Tübitak, 2021)Background/aim: The purpose of this study was to investigate the antiarthritic potentials of the inhibition of Src kinase in vivo and in vitro settings. Materials and methods: Arthritis was induced by intradermal injection ... -
Clinical manifestations of Behçet’s syndrome: A single-center cohort of 777 patients
(AVES, 2021)Behçet’s syndrome (BS) is a multisystem variable vessel vasculitis characterized by skin-mucosal lesions. It can also involve the eyes, blood vessels, joints, gastrointestinal system, urogenital system, and central nervous ... -
Mortality risk factors in patients with upper gastrointestinal bleeding in a medical intensive care unit
(Çukurova Üniversitesi, 2021)The aim of this study was to evaluate the general clinical characteristics of acute gastrointestinal system (GIS) bleeding patients who were followed-up in the intensive care unit (ICU) and the risk factors for mortality. ... -
Relationship between inflammatory markers and infection in chronic kidney disease
(Çukurova Üniversitesi, 2021)The aim of this study was to evaluate theimportance of C-reactive protein (CRP) and procalcitonin(PCT) in the diagnosis and monitoring of infections inchronic kidney disease (CKD) patients.Materials and Methods: In this ... -
Prevalence and influencing factors of anxiety in healthcare professionals in hemodialysis during the covid-19 pandemic
(AVES, 2021)During the COVID-19 pandemic, working in hemodialysis (HD) can be a source of anxiety. In this study, the anxiety status of HD healthcare professionals (HCPs) during the COVID-19 pandemic and the associated factors were ... -
Characteristics and mortality determinants of COVID-19 patients undergoing hemodialysis
(TÜBİTAK, 2021)The COVID-19 infection, which started in Wuhan City, China, in December 2019, turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-19 infections have ... -
Efficacy and safety of ruxolitinib in patients with myelofibrosis: a retrospective and multicenter experience in Turkey
(TÜBİTAK, 2021)The aim of this study is to assess the efficacy and safety of ruxolitinib in patients with myelofibrosis. Materials and methods: From 15 centers, 176 patients (53.4% male, 46.6% female) were retrospectively evaluated. ... -
Treatment patterns and associated clinical outcomes in type 2 diabetes patients ınitiating second-line glucose-lowering therapy: ınterim analysis of baseline data from turkey arm of the global dıscover study
(AVES, 2021)To evaluate the treatment patterns and associated clinical outcomes in Type 2 diabetes (T2D) patients initiating a second-line glucose-lowering the- rapy. Material and Methods: This paper presents a preliminary subgroup ... -
The relationship between strem-1 and activation of inflammatory bowel diseases
(İstanbul Üniversitesi, 2021)In inflammatory bowel disease (IBD), there is no re-liable biomarker, yet. We aimed to determine whether Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) could be useful as a marker for the diagnosis ... -
Clinical and demographic aspects of paget disease of bone: a multicentric study from Turkey
(AVES Yayıncılık, 2021)Paget disease of bone (PDB) is a metabolic bone disease that has been rarely reported in the Eastern countries. This study aimed to evaluate the clinical and demographic characteristics of patients with PDB followed up at ... -
Antiinflammatory and antioxidant effects of gemcitabine in collagen-induced arthritis model
(Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on ... -
Aggressive skin metastasis in lung cancer
(Turkish Assoc Tuberculosis & Thorax, 2018)A fifty seven year old male patient was admitted to our clinic because of complaints of cough and sputum. Computed tomography revealed by a 36x25 mm mass on the lateral of the 7th left rib, a 50x52 mm mass on the right ... -
Breast metastasis from squamous cell carcinoma of the cervix: a case report
(2015)Solid tümörlerin meme metastazına çok sık olmasa da klinik pratik hayatımızda rastlamaktayız ancak servikal kanserin memeye yayılımı literatürde de çok nadir bildirilmektedir. Olgumuz 65 yaşında, evre IV yassı hücreli ... -
Anti-TNF alfa kullanan hastalarda hepatit B reaktivasyonunun değerlendirilmesi
(2019)Amaç: Anti-tümör nekrozis faktör alfa (anti-TNF) alfa kullanan HBsAg pozitif hastalarda profilaksi önerilmektedir.HbsAg (-), anti-HBcIgG ( /-) ve anti-HBsIgG (-)hastalarda ise hepatit B profilaksisi tartışmalıdır. Bu ... -
BCR-ABL transcript tevel and neutrophil alkaline phosphatase activity in CML patients treated with ımatinib
(2010)Kronik ve ileri evre kronik miyeloid lösemili (KML) hastalarda imatinib mesilatın etkinliği gösterilmiştir. Bu çalışmada kronik faz da olan Türk KML hastaların 12 aylık imatinib mesilat tedavisine moleküler cevabın (BCR-ABL ... -
Bir bitki ekstresi olan ankaferd blood stopper®’in mycobacterium tuberculosis izolatlarına karşı in vitro etkinliği
(2013)Dirençli Mycobacterium tuberculosis enfeksiyonlarının tedavisi, toksik yan etkileri olan antitüberküloz ilaçların kombinasyonunu gerektirdiğinden, güvenli ve etkili yeni ilaçlara gereksinim vardır. Alpinia officinarum, ... -
Akut ve kronik böbrek yetmezliğinde mortalite nedenleri
(2011)Amaç: Akut ve kronik böbrek yetmezliği, ileri yaşla birlikte görülme insidansları giderek artan, mortalite oranları yüksek hastalıklardır. Çalışmamızın amacı, akut veya kronik böbrek yetmezliği nedeni ile hastanemize ...
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