2-Amino-4-(2-Naphthyl)Thiophene-3-Carbonitrile

Abstract

A new type of thiophene derivative with potential pharmacological activity, viz. 2-amino-4-(2-naphthalyl)thiophene-3-carbonitrile, C<inf>15</inf>H <inf>10</inf>N<inf>2</inf>S, has been prepared and studied by NMR and single-crystal X-ray diffraction techniques. The molecule contains two different groups, naphthalene and thiophene, which are nearly perpendicular to one another. In the crystal structure, a hydrogen bond, with a D⋯A distance of 3.033 (3) Å, is present between the amino substituent and the carbonitrile N atom of a symmetry-related molecule. The crystal structure also includes one C - H⋯π interaction. © 2005 International Union of Crystallography Printed in Great Britain - all rights reserved.