Use of Sugammadex in a Patient with Amyotrophic Lateral Sclerosis

Abstract

Objective: To report on general anesthesia management in amyotrophic lateral sclerosis. Case Presentation and Intervention: A 47-year-old man presented with fracture of the humerus. The patient was diagnosed with amyotrophic lateral sclerosis. General anesthesia was induced with propofol, rocuronium and remifentanil. After uneventful surgical repair, TOF (train-of-four) ratio reached >0.90 at the end of operation. However, muscle strength and tidal volume were inadequate. After sugammadex 2 mg kg-1 i.v. was given, the patient was extubated 120 s later. Conclusion: This case highlights that rocuronium and sugammadex can be used safely in patients with amyotrophic lateral sclerosis undergoing surgery with general anesthesia. Copyright © 2012 S. Karger AG, Basel.