Publication:
Phytochemical Screening, Anticancer and Antioxidant Activities of Origanum vulgare L. ssp. viride (Boiss.) Hayek, a Plant of Traditional Usage

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dc.authorscopusid55266006600
dc.authorscopusid6701658113
dc.authorscopusid55939045800
dc.authorscopusid56506698800
dc.authorscopusid6603661151
dc.contributor.authorKoldaş, S.
dc.contributor.authorDemirtaş, I.
dc.contributor.authorÖzen, T.
dc.contributor.authorDemirci, M.A.
dc.contributor.authorBehçet, L.
dc.date.accessioned2020-06-21T13:47:26Z
dc.date.available2020-06-21T13:47:26Z
dc.date.issued2015
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Koldaş] Serkan, Department of Chemistry, Çankiri Karatekin Üniversitesi, Cankiri, Turkey; [Demirtaş] Íbrahim, Department of Chemistry, Çankiri Karatekin Üniversitesi, Cankiri, Turkey; [Özen] Tevfik, Department of Chemistry, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Demirci] Mehmet Ali, Department of Chemistry, Çankiri Karatekin Üniversitesi, Cankiri, Turkey; [Behçet] Lütfi, Department of Biology, Bingöl Üniversitesi, Bingol, Turkeyen_US
dc.description.abstractBACKGROUND: A detailed phytochemical analysis of Origanum vulgare L. ssp. viride (Boiss.) Hayek was carried out and the antioxidant activities of five different crude extracts were determined. The antiproliferative activities of the extracts were determined using the xCELLigence system (Real Time Cell Analyzer). RESULTS: Differences between the essential oil and volatile organic compound profiles of the plant were shown. The main component of the essential oil was caryophyllene oxide, while the main volatile organic compounds were sabinene and eucalyptol as determined by HS-GC/MS. Phenolic contents of the extracts were determined qualitatively and quantitatively by HPLC/TOF-MS. Ten phenolic compounds were found in the extracts from O. vulgare and Origanum acutidens: rosmarinic acid (in highest abundance), chicoric acid, caffeic acid, p-coumaric acid, gallic acid, quercetin, apigenin-7-glucoside, kaempferol, naringenin and 4-hydroxybenzaldehyde. CONCLUSION: This study provides first results on the antiproliferative and antioxidant properties and detailed phytochemical screening of O. vulgare ssp. viride (Boiss.) Hayek. © 2014 Society of Chemical Industry.en_US
dc.identifier.doi10.1002/jsfa.6903
dc.identifier.endpage798en_US
dc.identifier.issn0022-5142
dc.identifier.issn1097-0010
dc.identifier.issue4en_US
dc.identifier.pmid25200133
dc.identifier.scopus2-s2.0-84922378210
dc.identifier.scopusqualityQ1
dc.identifier.startpage786en_US
dc.identifier.urihttps://doi.org/10.1002/jsfa.6903
dc.identifier.volume95en_US
dc.identifier.wosWOS:000349396000018
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Ltden_US
dc.relation.ispartofJournal of the Science of Food and Agricultureen_US
dc.relation.journalJournal of the Science of Food and Agricultureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectAntiproliferativeen_US
dc.subjectOriganum Acutidensen_US
dc.subjectOriganum vulgare ssp. virideen_US
dc.subjectPhenolicsen_US
dc.titlePhytochemical Screening, Anticancer and Antioxidant Activities of Origanum vulgare L. ssp. viride (Boiss.) Hayek, a Plant of Traditional Usageen_US
dc.typeArticleen_US
dspace.entity.typePublication

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