Publication:
A Rapid Detection of Multidrug-Resistant Mycobacterium Tuberculosis by a Nitrate Reductase Assay on Blood Agar

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dc.authorscopusid7007135107
dc.authorscopusid36479754000
dc.authorscopusid36730830100
dc.authorscopusid24921250000
dc.authorscopusid8888312400
dc.authorscopusid7003532093
dc.contributor.authorÇoban, A.Y.
dc.contributor.authorÇayci, Y.T.
dc.contributor.authorDeveci, A.
dc.contributor.authorAkgüneş, A.
dc.contributor.authorUzun, M.
dc.contributor.authorDurupínar, B.
dc.date.accessioned2020-06-21T14:40:15Z
dc.date.available2020-06-21T14:40:15Z
dc.date.issued2011
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Çoban] Ahmet Yilmaz, Department of Medical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Çayci] Yeliz Tanriverdi, Department of Medical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Deveci] Aydın, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Akgüneş] Alper, Department of Microbiology and Clinical Microbiology, Samsun Chest Diseases and Thoracic Surgery Hospital, Samsun, Samsun, Turkey; [Uzun] Meltem Önder, İstanbul Tıp Fakültesi, Istanbul, Turkey; [Durupínar] Belma, Department of Medical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractThe susceptibility of 49 Mycobacterium tuberculosis clinical isolates to isoniazid (INH) and rifampisin (RIF) (28 multi-drug resistant-tuberculosis samples) was determined by a nitrate reductase assay (NRA) on blood agar. Agreement between the NRA and other testing methods was found to be 93.8% for both INH and RIF. The sensitivity, specificity, positive predictive value and negative predictive value for INH were 92.8%, 94.2%, 86.6% and 97%, respectively. The sensitivity, specificity, positive predictive value and negative predictive value for RIF were 90.4%, 96.4%, 95% and 93.1%. In conclusion, we show here that blood agar can be used effectively for the NRA test.en_US
dc.identifier.doi10.1590/S0074-02762011000300022
dc.identifier.endpage380en_US
dc.identifier.issn0074-0276
dc.identifier.issn1678-8060
dc.identifier.issue3en_US
dc.identifier.pmid21655831
dc.identifier.scopus2-s2.0-79957967861
dc.identifier.scopusqualityQ2
dc.identifier.startpage378en_US
dc.identifier.urihttps://doi.org/10.1590/S0074-02762011000300022
dc.identifier.volume106en_US
dc.identifier.wosWOS:000291319200022
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherFundação Oswaldo Cruzen_US
dc.relation.ispartofMemórias Do Instituto Oswaldo Cruzen_US
dc.relation.journalMemorias Do Instituto Oswaldo Cruzen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlood Agaren_US
dc.subjectMycobacterium Tuberculosisen_US
dc.subjectNitrate Reductase Assayen_US
dc.titleA Rapid Detection of Multidrug-Resistant Mycobacterium Tuberculosis by a Nitrate Reductase Assay on Blood Agaren_US
dc.typeArticleen_US
dspace.entity.typePublication

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