Publication:
Comparative Effects of Propofol and Midazolam on Lipid Peroxidation and Antioxidant Agents

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dc.authorscopusid6507599026
dc.authorscopusid56216831400
dc.authorscopusid6602733768
dc.authorscopusid6701372559
dc.authorscopusid6701480599
dc.authorscopusid7006739343
dc.authorscopusid7006739343
dc.contributor.authorGokbulut, H.
dc.contributor.authorBariş, S.
dc.contributor.authorAmanvermez, R.
dc.contributor.authorSarıhasan, B.
dc.contributor.authorKarakaya, D.
dc.contributor.authorTür, A.
dc.contributor.authorÇelik, C.
dc.date.accessioned2025-12-11T02:01:40Z
dc.date.issued2000
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Gokbulut] H., Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Bariş] Sibel, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Amanvermez] Ramazan, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Sarıhasan] Binnur, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Karakaya] Deniz, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Tür] Ayla Hediye, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Çelik] Cemil, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractThe aim of this study is to compare propofol and midazolam for hemodynamic responses, lipid peroxidation products and antioxidant agents (superoxide-dismutase, glutation, total tiol). Twenty patients of ASA I-II randomized into two groups: propofol 2.5 mg/kg IV (Propofol Group) and midazolam 0.3 mg/kg IV (Midazolam Group) used as induction agents. Neuromuscular block was provided vecuronium 0.1 mg/kg in two groups. Anaesthesia was maintained with 1% isoflurane in 33% O<inf>2</inf> and 66% N<inf>2</inf>O. There was no statistically significance in hemodynamic parameters between the two groups. In the propofol group, serum lipid peroxide products, superoxide dismutase and glutation levels were significantly lower than the midazolam group. It is concluded that propofol is a scavenger of free oxygen radicals and cause a significant decrease in antioxidant agents.en_US
dc.identifier.endpage296en_US
dc.identifier.issn1016-5150
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-0033904706
dc.identifier.scopusqualityN/A
dc.identifier.startpage292en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12712/47618
dc.identifier.volume28en_US
dc.identifier.wosqualityN/A
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant Agentsen_US
dc.subjectFree Oxygen Radicalsen_US
dc.subjectPropofolen_US
dc.titleComparative Effects of Propofol and Midazolam on Lipid Peroxidation and Antioxidant Agentsen_US
dc.title.alternativePropofol ile Midazolaminin Lipid Peroksidasyonuna ve Antioksidanlara Etkilerinin Karşılaştırılmasıen_US
dc.typeArticleen_US
dspace.entity.typePublication

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