Product Operator Theory of 2D MAXY-HMQC NMR Spectroscopy for CDn Groups

Abstract

The product operator theory is widely used for analytical description of multi-pulse Nuclear Magnetic Resonance (NMR) experiments for weakly coupled spin systems. Two-dimensional liquid-state NMR experiments including edited-pulse angles such as DEPT-HMQC, MAXY-HMQC allow enhancing more information than conventional ones for weakly coupled spin systems in complex molecules. In this study, analytical descriptions of 2D MAXY-HMQC NMR experiment are performed using product operator theory for weekly coupled IS<inf>n</inf> (I = 1/2, S = 1; n = 1, 2, 3) spin systems. By using these results, theoretical discussions and experimental suggestions for sub-spectral editing of CD, CD<inf>2</inf>, and CD<inf>3</inf> groups are presented. © 2006 Elsevier B.V. All rights reserved.