Current Comments on Upper Gastrointestinal System Bleeding Data from a Research Hospital

Abstract

Upper gastrointestinal system (GIS) bleeding is one of the most common causes of hospitalization. This study aims to investigate the etiology of bleeding in patients admitted to Adana Numune Training and Research Hospital with the diagnosis of upper GIS bleeding. The study was conducted with 135 patients who applied for Upper GIS bleeding and underwent endoscopy between April and August 2005. This was a prospective study and all consecutive patients with upper GIS bleeding were included. Data were presented as ‘n, (%)’,’ mean ± standard deviation’. Of the patients 65.2% (n=88) were male, and the mean age was 56.7. The most common presenting symptoms were melena 44%(n=60), hematemesis 33% (n=45) and hematemesis+melena 16.3%(n=22). The most common etiologies were duodenal ulcer (35%, n=48), gastric ulcer (17%, n=23) and acute mucosal lesion (11%, n=15). Hp+ cases were 62.2% (n=84). Smoking was 28.1%(n=38), alcohol use was 13.3%(n=18). Of the patients 33% (n=45) had a history of previous Upper (GIS) bleeding, 52% (n=70) had ulcer-dyspepsia and 43% (n=58) had a history of NSAID use. Acetyl salicylic acid (ASA) was most commonly used as NSAID in 68.9%(n=40), flurbibrofen sodium in 39.6%(n=23), diclofenac in 29.3% (n=17) and multiple drugs in 39.6%(n=23). The reasons for taking ASA were cardiovascular protection in 55%(n=22).The use of NSAID’s accompanies upper GİS bleeding with ASA use is the most common. When using these drugs, their effects on upper GI bleeding should be taken into consideration. © 2025 Ondokuz Mayis Universitesi. All rights reserved.