Crystal Structure of a Mixed-Ligand Silver(I) Complex of the Non-Steroidal Anti-Inflammatory Drug Diclofenac and Pyrimidine

Abstract

In the title mixed-ligand silver(I) coordination polymeric complex with the non-steroidal anti-inflammatory drug diclofenac (C<inf>14</inf>H<inf>11</inf>Cl<inf>2</inf>NO<inf>2</inf>) (diclH) and pyrimidine (pym), namely poly[{μ2-2-[2-(2,6-dichloroanilino)phenyl]acetato-κ2 O:O′}(μ2-pyrimidine-κ2 N 1:N 3)silver(I)], [Ag(C<inf>14</inf>H<inf>10</inf>Cl<inf>2</inf>NO<inf>2</inf>)(C<inf>4</inf>H<inf>4</inf>N<inf>2</inf>)] n or [Ag(μ-dicl)(μ-pym)] n , the very distorted tetrahedral AgN<inf>2</inf>O<inf>2</inf> coordination centres comprise two N-atom donors from bridging pym ligands [Ag - N = 2.381 (3) and 2.412 (3) Å] and two carboxylate O-atom donors from dicl ligands [Ag - O = 2.279 (2) and 2.280 (2) Å], which bridge Ag atoms, giving a centrosymmetric dinuclear units with a short Ag⋯Ag separation [2.8931 (5) Å]. Within the units are short intraligand C - Cl⋯π(pym) interactions [3.6409 (15) Å]. The units are linked through the bridging N atoms of the pym ligand into a two-dimensional sheet-polymer structure lying parallel to (100) and stabilized by inter-ring π-π interactions between the pym ligands [Cg⋯Cg = 3.4199 (17) Å]. Additional inter-unit C - H⋯O and C - H⋯Cg hydrogen-bonding interactions between the sheets give an overall three-dimensional structure.