Publication: An Efficient Synthesis of (1S, 2R)-1-Amino-2-Indanol, a Key Intermediate of HIV Protease Inhibitor, Indinavir
| dc.contributor.author | Demir, Ayhan S. | |
| dc.contributor.author | Cam, Aksoy Hilal | |
| dc.contributor.author | Camkerten, Nurettin | |
| dc.contributor.author | Hamamcı, Haluk | |
| dc.contributor.author | Doğanel, Fatoş | |
| dc.date.accessioned | 2020-06-21T10:44:09Z | |
| dc.date.available | 2020-06-21T10:44:09Z | |
| dc.date.issued | 2000 | |
| dc.department | OMÜ | en_US |
| dc.department-temp | Ondokuz Mayıs Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, Samsun, Türkiye -- Girilmedi -- Girilmedi -- Girilmedi -- Girilmedi -- ONDOKUZ MAYIS ÜNİVERSİTESİ -- Tanımlanmamış Kurum | en_US |
| dc.description.abstract | (1S,2R)-l-amino-2-indanol, a key component of an HIV protease inhibitor is synthesized in four steps starting from indanone. The Mn(OAC)s mediated acetoxylation of indanone followed by fungus catalyzed hydrolysis of acetoxyindanone furnished optically pure a-hydroxy indanone. Formation and enantioselective reduction of oxime ether of 2-hydroxyindanone afforded (1S, 2R)-l-amino-2-indanol in 97% cis selectivity. | en_US |
| dc.identifier.endpage | 146 | en_US |
| dc.identifier.issn | 1300-0527 | |
| dc.identifier.issn | 1303-6130 | |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | 141 | en_US |
| dc.identifier.uri | https://app.trdizin.gov.tr/publication/paper/detail/TXpReU5qZzQ= | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12712/9712 | |
| dc.identifier.volume | 24 | en_US |
| dc.language.iso | en | en_US |
| dc.relation.journal | Turkish Journal of Chemistry | en_US |
| dc.relation.publicationcategory | Diğer | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Mühendislik | en_US |
| dc.subject | Kimya | en_US |
| dc.title | An Efficient Synthesis of (1S, 2R)-1-Amino-2-Indanol, a Key Intermediate of HIV Protease Inhibitor, Indinavir | en_US |
| dc.type | Other | en_US |
| dspace.entity.type | Publication |