Publication:
In Vitro Effect of Tigecycline Against Mycobacterium tuberculosis and a Review of the Available Drugs for Tuberculosis

dc.contributor.authorCoban, Ahmet Yilmaz
dc.contributor.authorDeveci, Aydin
dc.contributor.authorCayci, Yeliz Tanriverdi
dc.contributor.authorUzun, Meltem
dc.contributor.authorAkgunes, Alper
dc.contributor.authorDurupinar, Belma
dc.date.accessioned2020-06-21T14:41:02Z
dc.date.available2020-06-21T14:41:02Z
dc.date.issued2011
dc.departmentOMÜen_US
dc.department-temp[Coban, Ahmet Yilmaz -- Cayci, Yeliz Tanriverdi -- Durupinar, Belma] Ondokuz Mayis Univ, Sch Med, Dept Med Microbiol, Samsun, Turkey -- [Deveci, Aydin] Ondokuz Mayis Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Samsun, Turkey -- [Uzun, Meltem] Istanbul Univ, Istanbul Med Sch, Dept Med Microbiol, Istanbul, Turkey -- [Akgunes, Alper] Samsun Chest Dis Hosp, Clin Microbiol Lab, Samsun, Turkey --en_US
dc.description.abstractThe study aimed to investigate the effectiveness of a novel antibiotic drug tigecycline on clinical isolates of Mycobacterium tuberculosis and, reviewing defined anti-tuberculosis effects of available agents. Minimal inhibitory concentration (MIC) of tigecycline for 50 M. tuberculosis including multidrug-resistant (MDR) clinical isolates (20 MDR isolates) was determined by broth microdilution method in the study. Tigecycline MIC values were ranging between 8 and 64 mu g/ml. However, there is not any defined break point for M. tuberculosis resistance. In conclusion, it seems that the in vitro effectiveness of tigecycline to M. tuberculosis is not good but further in vivo studies are needed.en_US
dc.identifier.endpage315en_US
dc.identifier.issn1996-0808
dc.identifier.issue3en_US
dc.identifier.startpage311en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12712/17347
dc.identifier.volume5en_US
dc.identifier.wosWOS:000293693600017
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.journalAfrican Journal of Microbiology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjectTigecyclineen_US
dc.titleIn Vitro Effect of Tigecycline Against Mycobacterium tuberculosis and a Review of the Available Drugs for Tuberculosisen_US
dc.typeArticleen_US
dspace.entity.typePublication

Files