Publication: İmmünkompetan Hastada Görülen Dissemine Kriptokok İnfeksiyonu: İki Olgu
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Kriptokok infeksiyonları daha çok bağışıklığı baskılanmış hastalarda sporadik infeksiyon şeklinde görülür. Bu yazıda herhangi bir immünsüpresif durumu olmayan iki hastada görülen dissemine kriptokok infeksiyonu sunulmuştur. Olguların birinde akciğer infeksiyonu ve menenjit, diğerinde ise fungemi ve menenjit tespit edildi. Tedavide amfoterisin B ve flukonazol verildi. Hastalar uygun antifungal tedaviye rağmen kaybedildi. Biz bu olgularda, immünkompetan olmalarına rağmen kriptokok infeksiyonlarına bağlı mortalitenin yüksek olduğunu gözlemledik ve erken tanı ve tedavinin önemini vurgulamak istedik.
Cryptococcal infections usually manifest as sporadic infections in immunocompromised individuals. In this paper, two cases of disseminated cryptococcal infections in immunocompetent individuals have been presented. Both patients had meningitis, accompanied by pulmonary infection in one and fungemia in the other. Amphotericin B and fluconazole have been administered but both patients were lost despite pertinent antifungal treatment. Our objective was to point out the high mortality of cryptococcal infections even in immunocompetent patients and emphasize on the importance of early diagnosis and treatment.
Cryptococcal infections usually manifest as sporadic infections in immunocompromised individuals. In this paper, two cases of disseminated cryptococcal infections in immunocompetent individuals have been presented. Both patients had meningitis, accompanied by pulmonary infection in one and fungemia in the other. Amphotericin B and fluconazole have been administered but both patients were lost despite pertinent antifungal treatment. Our objective was to point out the high mortality of cryptococcal infections even in immunocompetent patients and emphasize on the importance of early diagnosis and treatment.
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Volume
17
Issue
3
Start Page
132
End Page
136
