Synthesis of a Cationic Ruthenium(II) Complex and Its Non-Enzymatic Glucose-Sensing Properties

Abstract

The new cationic ruthenium(II) complex (2) was synthesized via the reaction of N,N0-[1,10-(pyridine-2,6diyl)bis(ethan-1-yl-1-ylidene)]bis(2-ethyl-6-methylaniline) and [RuCl2(p-cymene)](2), and it was fully characterized using NMR, FT-IR, single-crystal X-ray diffraction, ESI-MS, UV-vis, CV and thermal analysis methods; theoretical computational characterizations and geometric parameters for 2 were also carried out via quantum chemical calculations using the density functional theory (DFT) method. In addition, the synthesized Ru(II) complex (2) was immobilized on fabricated RGO-TiO2@FTO to evaluate its nonenzymatic biosensing properties, and the sensing properties of the resulting Ru(II)-RGO-TiO2@FTO electrode were recorded. As a glucose-sensing model, at an applied potential of +0.34 V, the Ru(II)RGO-TiO2@FTO electrode presented a moderately good sensitivity of 62.69 mA mM(-1) cm(-1). Various modifications of Ru(II)-RGO-TiO2@FTO-type electrodes, such as the metal complex, and material types and ratios, will enable the design of future biosensor devices with improved performance.