Melatonin Use in Peripheral Nerve Injury

Abstract

Peripheral nerves consisting of clustered peripheral axons provide a common pathway to convey nerve impulses. Nerve injuries are generally classied depending on the degree of injury and symptoms as well (Turgut and Kaplan, 2011). Melatonin (Mel), the pineal neurohormone, has therapeutic effects on peripheral nerve regeneration in pathologic conditions or traumatic events (Odaci and Kaplan, 2009). In some current studies, a number of neuroscientists demonstrated that Mel has an effect on the morphologic features of the regenerating peripheral nerve tissue, which suggests its neuroprotective, free radical scavenging, antioxidative, and analgesic effects throughout that regeneration processes (Turgut and Kaplan, 2011). © 2015 by Taylor & Francis Group, LLC.