Effects of Aflatoxin and Various Adsorbents on Plasma Malondialdehyde Levels in Quails

Abstract

One-day-old 120 quail chicks (Coturnix coturnix japonica) were used in the study. The quails were divided into 10 equal groups. Group 1 was maintained as the control group. Groups 2, 3, 4, 5, 6, 7, 8, 9, and 10 were administered 2.5 ppm of aflatoxin, 2.5 ppm of aflatoxin+0.5% hydrated sodium calcium aluminosilicate (HSCAS), 0.5% HSCAS, 2.5 ppm of aflatoxin+0.5% yeast cell wall+oxicinol+tymol, 0.5% yeast cell wall+oxicinol+tymol, 2.5 ppm of aflatoxin+0.5% aluminosilicate+organic acid, 0.5% aluminosilicate+organic acid, 2.5 ppm of aflatoxin + 0.5% ammonium salts+HSCAS, and 0.5% ammonium salts+HSCAS, including various specialties, respectively. All three compounds were given in feed for a period of 21 d. At the end of the study, blood samples were collected from the animals into heparinized tubes for the detection of plasma malondialdehyde (MDA) levels. According to the obtained results, statistically significant differences were found in the MDA levels in groups 2, 7, and 9, in comparison with the control group. The highest level of MDA was detected in the group that was administered only aflatoxin. On the other hand, the values pertaining to the groups, which were administered with toxin binders in association with aflatoxin, were assessed to be close to the values of the control group. The groups that were administered only toxin binders, displayed values very close to those of the control group.