N-[5-Methyl-2-(2-Nitro-Phen-yl)-4-Oxo-1,3-Thia-Zolidin-3-yl]Pyridine-3-Carboxamide Monohydrate

Abstract

In the title compound, C<inf>16</inf>H<inf>14</inf>N<inf>4</inf>O <inf>4</inf>S·H<inf>2</inf>O, the benzene and pyridine rings make a dihedral angle of 85.8 (1)°. Both enantiomers of the chiral title compound are statistically disordered over the same position in the unit cell. The methyl and carbonyl group attached to the stereogenic center (C<inf>5</inf> of the thiazolidine ring) were therefore refined with common siteoccupation factors of 0.531 (9) and 0.469 (9), respectively, for each stereoisomer. In the crystal, intermolecular N -H⋯O, O -H⋯O and O -H⋯N hydrogen bonds link the molecules, forming a threedimensional supramolecular network. The crystal structure further shows π-π stacking interactions [centroidcentroid distance = 3.5063 (13) Å] between the pyridine rings.