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Acute Kidney Disease Beyond Day 7 After Major Surgery: A Secondary Analysis of the EPIS-AKI Trial

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dc.authorscopusid16203350300
dc.authorscopusid56666558100
dc.authorscopusid58647265700
dc.authorscopusid57948416100
dc.authorscopusid57218401073
dc.authorscopusid7006309884
dc.authorscopusid57869714100
dc.contributor.authorMeersch, M.
dc.contributor.authorWeiss, R.
dc.contributor.authorStrauss, C.
dc.contributor.authorAlbert, F.
dc.contributor.authorBooke, H.
dc.contributor.authorForni, L.
dc.contributor.authorPittet, J.
dc.date.accessioned2025-12-11T00:33:07Z
dc.date.issued2024
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Meersch] Melanie, Department of Anesthesiology, Universitätsklinikum Münster, Munster, Niedersachsen, Germany, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Weiss] Raphael, Department of Anesthesiology, Universitätsklinikum Münster, Munster, Niedersachsen, Germany, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Strauss] Christian, Department of Anesthesiology, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Albert] Felix, Institute of Biostatistics and Clinical Research, University of Münster, Munster, Nordrhein-Westfalen, Germany, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Booke] Hendrik, Department of Anesthesiology, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Forni] Lui G., School of Medicine, University of Surrey, Guildford, Surrey, United Kingdom, Intensive Care Unit, Royal Surrey Hospital, Guildford, Surrey, United Kingdom; [Pittet] Jean François, Department of Anesthesiology and Perioperative Medicine, Birmingham, AL, United States; [Kellum] John A., Center for Critical Care Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; [Rosner] Mitchell Howard, University of Virginia School of Medicine, Charlottesville, VA, United States; [Mehta] Ravindra L., Department of Medicine, La Jolla, CA, United States; [Bellomo] Rinaldo, Department of Critical Care, Melbourne, VIC, Australia, Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia, Department of Intensive Care, Austin Health, Melbourne, VIC, Australia, Monash University, Melbourne, VIC, Australia; [Rosenberger] Peter, Department of Anaesthesia and Intensive Care, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Zarbock] Alexander, Department of Anesthesiology, Universitätsklinikum Münster, Munster, Niedersachsen, Germany, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Makhloufi] Hichem, Centre Hospitalier Universitaire, Algiers, Alger, Algeria; [Sakhraoui] Rachida, Etablissement Hospitalier Spécialisé Salim Zemirli El Harrach, Algiers, Algeria; [Ouyahia] Amel A., Saadna Abdenour Teaching Hospital, Algiers, Setif, Algeria; [Rais] Mounira M., Saadna Abdenour Teaching Hospital, Algiers, Setif, Algeria; [Kouicem] Aya Tinhinane, Saadna Abdenour Teaching Hospital, Algiers, Setif, Algeria; [Derwish] Khawla, Sabratha Libya National Cancer Institute, Algiers, Algeria, National Cancer Institute, Sabratha, Libya; [Abdoun] Meriem, University Hospital of Setif, Algiers, Setif, Algeria; [Ouahab] Ilhem, University Hospital of Setif, Algiers, Setif, Algeria; [Bouaoud] Souad, University Hospital of Setif, Algiers, Setif, Algeria; [Tidjane] Anisse, Centre Hospitalier - Universitaire d'Oran, Oran, Oran Province, Algeria; [Pérez Rivera] Carlos José, Universidad El Bosque, Bogota, Colombia; [García] Juan Pablo, Universidad El Bosque, Bogota, Colombia; [Peng] Ke, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China; [Ji] Fuhai, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China; [Ma] Zhengmin, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China; [Elbahnasawy] Mohamed Gamal, Faculty of Medicine, Tanta, Gharbia, Egypt; [Elsalhawy] Shady, Faculty of Medicine, Tanta, Gharbia, Egypt; [Nafea] Ahmed Mahmoud, Alexandria University, Alexandria, Alexandria, Egypt; [Osman] Nermin A., Alexandria University, Alexandria, Alexandria, Egypt; [Maher Emara] Moataz Maher, Faculty of Medicine, Mansoura, Dakahlia, Egypt; [Bonna] Mohamed Mamdouh, Faculty of Medicine, Mansoura, Dakahlia, Egypt; [Abdehaleem] Ibrahim Abdelmonaem, Zagazig University Hospitals, Zagazig, Sharqia, Egypt; [Abbas] Ahmed M., Assiut University, Asyut, Asyut, Egypt; [Abbas] Mostafa Samy, Assiut University, Asyut, Asyut, Egypt; [Osman] Hany M., Assiut University, Asyut, Asyut, Egypt; [Joannès-Boyau] Olivier, Centre Hospitalier, France, France; [Legros] Vincent, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Floch] Thierry, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Muccio] Salvatore, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Menage-Innocenti] Lison, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Brochet] Benjamin, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Leclercq-Rouget] Marion, Université de Reims Champagne-Ardenne, Reims, Grand Est, France; [Geneve] Claire, Centre Hospitalier, France, France; [Mocarquer] Bernardita Valenzuela, Centre Hospitalier, France, France; [Aveline] Christophe, Hôpital Privé Sévigné, Cesson-Sevigne, France; [Vautier] Pierre, Hôpital Privé Sévigné, Cesson-Sevigne, France; [Nadaud] Julien, Hôpital Robert Schuman-Groupe UNEOS, France; [Rimmelé] Thomas R., Hopital Edouard Herriot, Lyon, France; [Cerro] Valérie, Hopital Edouard Herriot, Lyon, France; [Suria] Stéphanie, Gustave Roussy, Vellejuif, France; [Elmawieh] Jamie, Gustave Roussy, Vellejuif, France; [El-Jawiche] Rita, Gustave Roussy, Vellejuif, France; [Cirenei] Cedric, Université de Lille, Lille, Hauts-de-France, France; [Lebuffe] Gilles R., Université de Lille, Lille, Hauts-de-France, France; [Ponsonnard] Sebastien, Clinique François Chénieux, Limoges, France; [Egreteau] Pierre Yves, Centre Hospitalier des Pays de Morlaix, Gilly, France; [Ichaï] Carole R., Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Jean-Michel] Vanessa, Dron Hospital of Tourcoing, Tourcoing, France; [Léger] Maxime, Centre Hospitalier Universitaire d’Angers, France; [Lasocki] Sigismond, Centre Hospitalier Universitaire d’Angers, France; [Masson] Charline, Centre Hospitalier Universitaire d’Angers, France; [Rineau] Emmanuel, Centre Hospitalier Universitaire d’Angers, France; [Cassisa] Viviane, Centre Hospitalier Universitaire d’Angers, France; [Verrier] Pierre, Centre François Baclesse, Caen, France; [Atchade] Enora, Hôpital Bichat-Claude-Bernard AP-HP, Paris, France; [Rochon] Charles Edouard, Centre Hospitalier, France, France; [Quentin] Vidal, Centre Hospitalier de Bigorre, Tarbes, France; [Queixalos] Nina, Centre Hospitalier Universitaire de Bordeaux, Talence, Nouvelle-Aquitaine, France; [Braun] Thierry, Clinique Sainte-Anne, Strasbourg, France; [Grand] Hubert, Centre Hospitalier de Libourne, Libourne, France; [Mayeur] Nicolas, Clinique Pasteur, Toulouse, France; [Pasquié] Marie, Clinique Pasteur, Toulouse, France; [Garçon] Pierre, Centre Hospitalier de Marne-la-Vallée, Marne-la-Vallee, France; [Bruckert] Vincent, Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Pradel] Gaël, Centre Hospitalier Henri Mondor d’Aurillac, France; [Ramorasata] Andersen, Centre Hospitalier de Mont de Marsan, Mont-de-Marsan, France; [Ravry] Céline, Centre Hospitalier de Dax, Dax, France; [Mottard] Nicolas, Clinique de la Sauvegarde, Lyon, France; [von Groote] Thilo Caspar, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Dörr] Christian, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Küllmar] Mira, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Massoth] Christina, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Motekallemi] Arash, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Saadat-Gilani] Khaschayar, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Kerschke] Laura, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Storck] Michael, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Varghese] Julian, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Wempe] Carola, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Grüsser] Linda, Uniklinik RWTH Aachen, Aachen, Nordrhein-Westfalen, Germany; [Kowark] Ana, Uniklinik RWTH Aachen, Aachen, Nordrhein-Westfalen, Germany; [Brandenburger] Timo, Universitätsklinikum Düsseldorf, Dusseldorf, Nordrhein-Westfalen, Germany; [Hohn] Andreas, Kliniken Maria Hilf GmbH, Monchengladbach, Nordrhein-Westfalen, Germany; [Häeberle] Helene Anna, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Hofmann] Pascal, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Kuhle] Jonathan, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Calov] Stefanie, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Bernard] Alice Marie, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Mirakaj] Valbona, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Weber] Kathrin, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Pfister] Kathrin, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Stetz] Lena, Universitätsklinikum und Medizinische Fakultät Tübingen, Tubingen, Baden-Wurttemberg, Germany; [Müller] Sarah Dorothea, Universitätsklinikum Leipzig und Medizinische Fakultät, Leipzig, Sachsen, Germany; [Klaus] Stephan, Herz-Jesu-Krankenhaus Münster-Hiltrup, Munster, Nordrhein-Westfalen, Germany; [Sadlo] Marco, Herz-Jesu-Krankenhaus Münster-Hiltrup, Munster, Nordrhein-Westfalen, Germany; [Sengelhoff] Christian, St. Josef-Stift SendenHorst, Sendenhorst, Nordrhein-Westfalen, Germany; [Stenger] Carina Kristin, Sankt Franziskus Hospital, Koln, Germany; [Goebel] Ulrich Michael, Sankt Franziskus Hospital, Koln, Germany; [Heringlake] Matthias, Hosspital Karlsburg, Karlsburg, Germany; [Αrnaoutoglou] Eleni M., University Hospital of Larissa, Larissa, Greece; [Stratigopoulou] Panagiota, Laikon General Hospital, Athens, Attica, Greece; [Danai] Pantazi, University General Hospital of Ioannina, Ioannina, Epirus, Greece; [Dimakopoulou] Antonia N., G. Gennimatas General Hospital, Athens, Greece; [Menis] Apostolos Alkiviadis, Hippokration General Hospital of Thessaloniki, Thessaloniki, Central Macedonia, Greece; [Ioannidis] Orestis M., Aristotle University of Thessaloniki, Thessaloniki, Central Macedonia, Greece; [Jalaawiy] Humam, Al-Diwaniyah Teaching Hospital, Diwaniyah, Al Qadisiyah, Iraq; [Anwar] Aeshah, Baghdad Teaching Hospital, Baghdad, Iraq; [Talib] Hashim Talib, Al-Nassiryah Teaching Hospital, Thi Qar, Iraq; [Rasheed Aldawoody] Hogir Imad, Khanaqeen General Hospital, Khanaqin, Iraq; [Cortegiani] Andrea, Policlinico Paolo Giaccone, Italy; [Ippolito] Mariachiara, Policlinico Paolo Giaccone, Italy; [Marino] Claudia, Policlinico Paolo Giaccone, Italy; [Presti] Gabriele, Policlinico Paolo Giaccone, Italy; [Fricano] Dario Calogero, Policlinico Paolo Giaccone, Italy; [De Rosa] Silvia, Ospedale San Bortolo, Vicenza, VI, Italy; [Bianchin] Andrea, Civic Hospital of Montebelluna, Montebelluna, Veneto, Italy; [Paternoster] G., San Carlo Regional Hospital, Potenza, Basilicata, Italy; [Fasciano] Umberto, San Carlo Regional Hospital, Potenza, Basilicata, Italy; [Cutuli] Salvatore Lucio, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio, Italy; [Savino] Spadaro, University of Ferrara, Ferrara, FE, Italy; [Enrico] Bussolati, University of Ferrara, Ferrara, FE, Italy; [Marco] Palmieri, University of Ferrara, Ferrara, FE, Italy; [Alberto] Volta Carlo, University of Ferrara, Ferrara, FE, Italy; [Tripodi] Vincenzo Francesco, Great Metropolitan Hospital "Bianchi-Melacrino-Morelli", Reggio, Calabria, Italy; [Fiume] Diego, Sant’Eugenio Hospital, Italy; [Iuorio] Angela, Frangipane Hospital, Ariano Irpino, Italy; [Santorsola] Clemente, General Hospital Vallecamonica, Italy; [Abu-Hussein] Bilal, Al-Basheer Hospital, Amman, Amman, Jordan; [Hasanein] Khaled, Al-Basheer Hospital, Amman, Amman, Jordan; [Shin] Seokyung, Yonsei University College of Medicine, Seoul, South Korea; [Baek] Jongyoon, Yeungnam School of Medicine, Yeungnam University Hospital, Daegu, South Korea; [Kim] Sehui, Yeungnam School of Medicine, Yeungnam University Hospital, Daegu, South Korea; [Elhadi] Muhammed K., University of Tripoli, Tripoli, Libya; [Aldressi] Wafa O., Benghazi Medical Center, Benghazi, Libya; [Abuzeid] Issa A., Benghazi Medical Center, Benghazi, Libya; [Albaraesi] Mohammed N., Benghazi Medical Center, Benghazi, Libya; [Moftah] Mohamed Aziz, Benghazi Medical Center, Benghazi, Libya; [Aldressi] Sarah, Benghazi Medical Center, Benghazi, Libya; [Khalel] Wegdan Ibrahim Almabrouk, Tripoli Central Hospital, Tripoli, Libya; [Abdulwahed] Eman Ali, Tripoli Central Hospital, Tripoli, Libya; [Ali Alshareea] Entisar Ahmed, Tripoli Central Hospital, Tripoli, Libya; [Abujrad Reem Ghmagh] Akram Abdulhamid Ashur, Tripoli Central Hospital, Tripoli, Libya; [Biala] Marwa Isa, Tripoli Central Hospital, Tripoli, Libya; [Benjouira] Rayet Al Islam, National Heart Center, Tripoli, Libya; [Aliwa] Mohamed, National Heart Center, Tripoli, Libya; [Msherghi] Ahmed A.A., University Hospital, Tripoli, Libya; [Tuwaib] Ahmed, University Hospital, Tripoli, Libya; [Mustafa] Tahani, University Hospital, Tripoli, Libya; [Zriba] Haifa, University Hospital, Tripoli, Libya; [Agilla] Hamza Mahmoud, AboSleem Hospital, Tripoli, Libya; [Sadek Ben Hamida] Bahaeddin Taher, El-Khadra Hospital, Tripoli, Tripoli, Libya; [Mohamed Otman] Rema Hassan, El-Khadra Hospital, Tripoli, Tripoli, Libya; [Mijovska] Maja Mojsova, University Mother Theresa, Skopje, Skopje, North Macedonia; [Podesta] Anne Marie Camilleri, Mater Dei Hospital, Valletta, VLT, Malta; [Gasca-López] Gilberto Adrián, High Specialty Regional Hospital of Ixtapaluca, Iztapalapa, MEX, Mexico; [Amro] Sarah, Princess Alia Governmental Hospital, Palestine; [de Freitas Regufe] Rita, Central Hosptial of Setúbal, Hospital de São Bernardo, Setubal, Portugal; [Grigoriev] Evgeny V., Kuzbass Cardiology Center SB RAS, Kemerovo, Kemerovo Oblast, Russian Federation; [Ivkin] A. A., Kuzbass Cardiology Center SB RAS, Kemerovo, Kemerovo Oblast, Russian Federation; [Balakhnin] Dmitry G., Kuzbass Cardiology Center SB RAS, Kemerovo, Kemerovo Oblast, Russian Federation; [Shukevich] Dmitriy Leonidovich, Kuzbass Cardiology Center SB RAS, Kemerovo, Kemerovo Oblast, Russian Federation; [Yaroustovsky] M. B., A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow, Moscow, Russian Federation; [Barmou] Abdulnaser, Almanea General Hospital Al Khobar, Al-Khobar, Ash Sharqiyah, Saudi Arabia; [Kaserer] Alexander, UniversitatsSpital Zurich, Zurich, ZH, Switzerland; [Castellucci] Clara, UniversitatsSpital Zurich, Zurich, ZH, Switzerland; [Akbas] Samira, UniversitatsSpital Zurich, Zurich, ZH, Switzerland; [Petrun] Andreja Möller, Univerzitetni Klinični Center Maribor, Maribor, Slovenia; [Gregorcic] Irena, Univerzitetni Klinični Center Maribor, Maribor, Slovenia; [Sok] Vesna, Univerzitetni Klinični Center Maribor, Maribor, Slovenia; [Links] Andre, Stellenbosch University, Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa; [Barreto] Elizabeth Bárcena, Complejo Hospitalario Universitario de Granada, Granada, Granada, Spain; [Melchor] Javier Ripollés, Hospital Universitario Infanta Leonor, Madrid, Madrid, Spain; [Becerra] Angel, Hospital de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Las Palmas, Spain; [Rodriguez-Perez] A., Hospital de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Las Palmas, Spain; [Estévez] Javier Mata, Son Llatzer University Hospital, Spain; [Matas] Juan Mulet, Son Llatzer University Hospital, Spain; [Palao] Sara Pérez, Son Llatzer University Hospital, Spain; [Álvarez] Mercedes García, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Albadalejo] Albert Bainac, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [González] Astrid Batalla, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Caro] Ana María Gómez, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Blanco] Ignacio Hinojal, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Fernández] Diego Toral, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Perez] Gracia Herranz, Hospital de La Santa Creu I Sant Pau, Barcelona, Barcelona, Spain; [Ejea] Margarita Logroño, Hospital Universitario Araba, Vitoria-Gasteiz, Alava, Spain; [de la Rosa Ruiz] Noelia, Hospital Universitario Araba, Vitoria-Gasteiz, Alava, Spain; [Abasolo] María Gastaca, Hospital Universitario Araba, Vitoria-Gasteiz, Alava, Spain; [Ferreira] Lourdes, Hospital San Pedro, Logrono, La Rioja, Spain; [Lobato] Félix, Hospital San Pedro, Logrono, La Rioja, Spain; [Sevilla] Marta Aguado, Hospital San Pedro, Logrono, La Rioja, Spain; [Erazo] Andres, Fundacio Puigvert, Barcelona, Barcelona, Spain; [Paulis] Berta Castellano, Hospital, Donostia-San Sebastian, Spain; [De-La-Calle-Gil] Isabel, Hospital Universitario 12 de Octubre, Madrid, Madrid, Spain; [Adamove] Peter, University Hospital of Bellvitge, Catalonia, Spain; [Blasco] Francho Miguel, University Hospital of Bellvitge, Catalonia, Spain; [García Sánchez] José Ignacio, Hospital Universitario Fundación Alcorcón, Alcorcon, Madrid, Spain; [Zamorano] Sara García, Hospital Universitario Fundación Alcorcón, Alcorcon, Madrid, Spain; [Herreros] Natalia Gijón, Hospital Universitario Fundación Alcorcón, Alcorcon, Madrid, Spain; [Callejas] Raquel, Clínica Universidad de Navarra, Pamplona, Navarre, Spain; [Gómez] Mercedes Estaire, Ciudad Real University Hospital, Ciudad Real, Spain; [Candela-Toha] Angel Manuel, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Claros-Llamas] Elisabeth, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Cobeta Orduña] Pilar, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Crespo-Aliseda] Pascual Agustín, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Dorado Díaz] Trinidad, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Gómez-Rojo] María, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Mané-Ruiz] M. Nuria, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [González] M. Carmen Martín, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Martínez Pérez] Adolfo, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Tiscar] Carlos, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain; [Menendez] Patricia Galán, Vall d’Hebron University Hospital, Spain; [Calvo] Verónica Estepa, Vall d’Hebron University Hospital, Spain; [Espí] Laura Llinares, Vall d’Hebron University Hospital, Spain; [Aldeán] Yuri Loaiza, Vall d’Hebron University Hospital, Spain; [Ariza] Víctor Morales, Vall d’Hebron University Hospital, Spain; [Vila] Laura Villarino, Vall d’Hebron University Hospital, Spain; [García-Miguel] Francisco Javier, La Gerencia de Asistencia Sanitaria de Segovia, Segovia, Spain; [Suliman] Elfayadh Saidahmed Mohamed, Sharg Alneel Hospital & Omdurman Military Hospital, Omdurman, Sudan; [Ibrahim] Ahmed Mohamed, Gadarif Teaching Hospital, El-Gadarif, Sudan; [Fadlalmola] Hammad Ali, Ahmed Gasim Hospital, Sudan; [Swed] Sarya, Syria Faculty of Medicine, Free Aleppo University, Aleppo, Aleppo, Syrian Arab Republic; [Wu] Vincent, National Taiwan University Hospital, Taipei, Taiwan; [Orhan-Sungur] Mukadder, İstanbul Tıp Fakültesi, Istanbul, Turkey; [Altun] Demet, İstanbul Tıp Fakültesi, Istanbul, Turkey; [Canbolat] Nur, İstanbul Tıp Fakültesi, Istanbul, Turkey; [Dinçer] Muserref Beril, İstanbul Tıp Fakültesi, Istanbul, Turkey; [Aktas Yildirim] Serap, Acibadem Mehmet Ali Aydinlar University School of Medicine, Acibadem, Turkey; [Iyigün] Müzeyyen, Acibadem Mehmet Ali Aydinlar University School of Medicine, Acibadem, Turkey; [Yapici] D., Mersin Üniversitesi, Mersin, Turkey; [Özdemir] Levent, Mersin Üniversitesi, Mersin, Turkey; [Sagün] Aslınur, Mersin Üniversitesi, Mersin, Turkey; [Boztuǧ] Neval, Akdeniz Üniversitesi, Antalya, Turkey; [Gündüz] Emel, Akdeniz Üniversitesi, Antalya, Turkey; [Lafli-Tunay] Demet, Çukurova Üniversitesi, Adana, Adana, Turkey; [Karakaya] Deniz, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Dost] Burhan, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Kömürcü] Özgür, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Korkmaz Dilmen] Özlem Korkmaz, Istanbul University-Cerrahpasa, Istanbul, Turkey; [Akçil] Eren Fatma, Istanbul University-Cerrahpasa, Istanbul, Turkey; [Tunali] Yusuf, Istanbul University-Cerrahpasa, Istanbul, Turkey; [Ok] Gülary, Manisa Celâl Bayar Üniversitesi, Manisa, Manisa, Turkey; [Tok-Alsina] Eda, Manisa Celâl Bayar Üniversitesi, Manisa, Manisa, Turkey; [Polat] Cengiz, Cemil Taşcıoğlu City Hospital, Turkey; [Kizilcik] Nurcan, Yeditepe University, Istanbul, Turkey; [Şen] Öznur, Haseki Training and Research Hospital, Haseki, Turkey; [Darçin] Kamil M.D., Koç University, Istanbul, Turkey; [Uğur] Semra, Koç University, Istanbul, Turkey; [Gürkan] Yavuz M.D., Koç University, Istanbul, Turkey; [Saraçoǧlu] Kemal Tolga, Kartal Dr. Lütfi Kırdar City Hospital, Kartal, Istanbul, Turkey; [Yıldız-Koyuncu] Özge, Kartal Dr. Lütfi Kırdar City Hospital, Kartal, Istanbul, Turkey; [Demir] Asli Z., Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Postaci] Aysun, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Özgök] Ayşegül, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Karadeniz] Ümit, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Özay] Hulya Yigit, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Balcı] Eda, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Salman] Nevriye, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Girgin] Behic, Ankara Bilkent City Hospital, Ankara, Ankara, Turkey; [Saǧir] Özlem, Balikesir Üniversitesi, Balikesir, Balikesir, Turkey; [Demir] Hafize Fisun, Balikesir Üniversitesi, Balikesir, Balikesir, Turkey; [Ugün] Fatih, Balikesir Üniversitesi, Balikesir, Balikesir, Turkey; [Toprak] Hüseyin I., Inönü Üniversitesi, Malatya, Turkey; [Özcan] Mustafa Soner, Süleyman Demirel Üniversitesi, Isparta, Isparta, Turkey; [Alkaya-Solmaz] Filiz, Süleyman Demirel Üniversitesi, Isparta, Isparta, Turkey; [Yilmaz] Mehmet Ufuk, Kocaeli Derince Training and Research Hospital, Derince, Kocaeli, Turkey; [Karaca] Umran, Bursa Yüksek lhtisas Training and Research Hospital, Bursa, Turkey; [Hekimoǧlu Şahin] Sevtap, Trakya Üniversitesi, Edirne, Edirne, Turkey; [Erkoç] Süheyla Karadaǧ, Ankara Üniversitesi, Ankara, Turkey; [Alkiş] Neslihan, Ankara Üniversitesi, Ankara, Turkey; [Baytaş] Volkan, Cebeci Hospital, Cebeci, Turkey; [Erturk] E., Karadeniz Technical University, Trabzon, Trabzon, Turkey; [Saylan] Sedat, Karadeniz Technical University, Trabzon, Trabzon, Turkey; [Akdoǧan] Ali, Karadeniz Technical University, Trabzon, Trabzon, Turkey; [Yeşil] Beyza Büyükgebiz, Gazi Üniversitesi, Ankara, Ankara, Turkey; [Boran] Omer Faruk, Kahramanmaraş Sütcü Imam university faculty of medicine, Kahramanmaras, Kahramanmaraş, Turkey; [Orak] Yavuz, Kahramanmaraş Sütcü Imam university faculty of medicine, Kahramanmaras, Kahramanmaraş, Turkey; [Çalışır] Feyza, Kahramanmaraş Sütcü Imam university faculty of medicine, Kahramanmaras, Kahramanmaraş, Turkey; [Büyükcoban] Sibel, Dokuz Eylül Üniversitesi, Izmir, Turkey; [Balkan] Bahar Kuvaki, Dokuz Eylül Üniversitesi, Izmir, Turkey; [Cansabuncu] Seda, Bursa Uludağ Üniversitesi, Bursa, Bursa, Turkey; [Akesen] Selcan, Bursa Uludağ Üniversitesi, Bursa, Bursa, Turkey; [Gören] Suna, Bursa Uludağ Üniversitesi, Bursa, Bursa, Turkey; [Yeniocak] Tugce, Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Annaba, Turkey; [Orman] Osman, Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Annaba, Turkey; [Karka] Özlem Ersoy, Düzce Üniversitesi, Duzce, Turkey; [Yildiz] Tülay Şahin, Kocaeli Üniversitesi, İzmit, Kocaeli, Turkey; [Momot] Natalia V., Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Zaporizhia Oblast, Ukraine; [Panchenko] Anna, Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Zaporizhia Oblast, Ukraine; [Rutledge] Kristen M., University of Alabama, Tnscaloosa, AL, United Statesen_US
dc.description.abstractPurpose: Acute kidney disease (AKD) is a significant health care burden worldwide. However, little is known about this complication after major surgery. Methods: We conducted an international prospective, observational, multi-center study among patients undergoing major surgery. The primary study endpoint was the incidence of AKD (defined as new onset of estimated glomerular filtration rate (eCFR) < 60 ml/min/1.73 m2 present on day 7 or later) among survivors. Secondary endpoints included the relationship between early postoperative acute kidney injury (AKI) (within 72 h after major surgery) and subsequent AKD, the identification of risk factors for AKD, and the rate of chronic kidney disease (CKD) progression in patients with pre-existing CKD. Results: We studied 9510 patients without pre-existing CKD. Of these, 940 (9.9%) developed AKD after 7 days of whom 34.1% experiencing an episode of early postoperative-AKI. Rates of AKD after 7 days significantly increased with the severity (19.1% Kidney Disease Improving Global Outcomes [KDIGO] 1, 24.5% KDIGO2, 34.3% KDIGO3; P < 0.001) and duration (15.5% transient vs 38.3% persistent AKI; P < 0.001) of early postoperative-AKI. Independent risk factors for AKD included early postoperative-AKI, exposure to perioperative nephrotoxic agents, and postoperative pneumonia. Early postoperative-AKI carried an independent odds ratio for AKD of 2.64 (95% confidence interval [CI] 2.21–3.15). Of 663 patients with pre-existing CKD, 42 (6.3%) had worsening CKD at day 90. In patients with CKD and an episode of early AKI, CKD progression occurred in 11.6%. Conclusion: One in ten major surgery patients developed AKD beyond 7 days after surgery, in most cases without an episode of early postoperative-AKI. However, early postoperative-AKI severity and duration were associated with an increased rate of AKD and early postoperative-AKI was strongly associated with AKD independent of all other potential risk factors. © The Author(s) 2024.en_US
dc.identifier.doi10.1007/s00134-023-07314-2
dc.identifier.endpage257en_US
dc.identifier.issn0342-4642
dc.identifier.issn1432-1238
dc.identifier.issue2en_US
dc.identifier.pmid38285051
dc.identifier.scopus2-s2.0-85183393467
dc.identifier.scopusqualityQ1
dc.identifier.startpage247en_US
dc.identifier.urihttps://doi.org/10.1007/s00134-023-07314-2
dc.identifier.urihttps://hdl.handle.net/20.500.12712/37334
dc.identifier.volume50en_US
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media Deutschland GmbHen_US
dc.relation.ispartofIntensive Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute Kidney Diseaseen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectChronic Kidney Diseaseen_US
dc.subjectPostoperativeen_US
dc.subjectSurgeryen_US
dc.titleAcute Kidney Disease Beyond Day 7 After Major Surgery: A Secondary Analysis of the EPIS-AKI Trialen_US
dc.typeArticleen_US
dspace.entity.typePublication

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