Publication:
2-{2-[4-(4-Fluoro-Phen-yl)Piperazin-1-yl]-2-Oxoeth-yl}-6-(Morpholin-4-yl)-4-Phenyl-Pyridazin-3(2H)-One

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In the title compound, C<inf>26</inf>H<inf>28</inf>FN<inf>5</inf>O <inf>3</inf>, the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q<inf>T</inf> = 0.5437 (15) Å, θ = 8.89 (15) and φ = 357.2 (11)°]. The 1,6-dihydropyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)° with the phenyl and benzene rings, respectively. In the crystal, molecules are linked along the c axis by C - H⋯O interactions and are flattened parallel to the ac plane. C - H⋯π interactions also contribute to the stability of the structure.

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Acta Crystallographica Section E: Structure Reports Online

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67

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3

Start Page

o666

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o667

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