Sperm DNA Damage and Oocyte Repair Capability

Abstract

The integrity and stability of the sperm genome is protected by DNA repair mechanisms both in the male germ line cells and oocyte. This chapter focuses on our understanding of DNA repair mechanisms in the oocyte and zygote after fertilization. The chapter also reviews the origin of DNA damage, the effect of sperm DNA damage on reproductive outcomes and sperm selection methods in assisted reproductive techniques. © Springer International Publishing AG 2018.