Evaluation of Infective Endocarditis Agents

Abstract

Endocarditis is an inflammation or microbial infection of the heart valves and the endocardium of the heart. Bacteria that enter the blood due to various reasons can multiply in the endocardial layer of the heart and cause infection. In addition, these infections can be carried to different parts of the body through the bloodstream. This study aims to evaluate the distribution of microorganisms grown in blood cultures taken from patients diagnosed with endocarditis. The distribution of microorganisms grown in blood culture samples sent from patients diagnosed with endocarditis to our Ondokuz Mayıs University Medical Microbiology Laboratory between 2018-2021 was retrospectively examined. The distributions of the most frequently isolated bacteria from 63 strains obtained from blood samples are as follows; 61.90% Staphylococcus spp., 11.11% Streptococcus spp., 9.52% Enterococcus spp., 3.17% Escherichia coli, 1.58% Enterobacter cloacae, 6.34% Klebsiella pneumoniae, 1.58% Acinetobacter baumannii, 1.58% Stenotrophonomonas maltophilia, 1.58% Corynebacterium stratum, 1 1.58% Micrococcus spp. Oxacillin resistance was detected as 44.44% in S. aureus isolates. Carbapenem resistance was not detected in Enterobactarales bacteria. Vancomycin resistance was not detected in enterococcus isolates. Despite significant developments in the diagnosis and treatment of infective endocarditis, there has been no decrease in its incidence and mortality. Similar to many articles in the literature, it has been determined that the most frequently isolated pathogen is S. aureus. Knowing the distribution of infective endocarditis agents is important in guiding clinicians in both prophylactic and empirical treatment selection. © 2025, Ondokuz Mayis Universitesi. All rights reserved.