Magnetic Nanoparticles for Diagnosis and Treatment

Abstract

Cancer is a complex disease in which certain cells in the body grow uncontrollably and spread to other parts of the body. Although there have been advances observed in\rthe diagnosis and treatment of cancer, many studies are conducted to eliminate the side effects that occur during treatment. Magnetic nanoparticles (MNPs) are of great\rinterest in the field of cancer diagnosis and treatment due to their magnetic features, biocompatibility, and stability. These features allow them to be used as a contrast agent\rfor magnetic resonance (MR) imaging as a therapeutic system with a drug release system and hyperthermia. MNP-based imaging, drug release systems, and hyperthermia\rtreatments have been studied by researchers and reported to be promising for the treatment of various types of cancer. Although the clinical applications of MNPs for\rcancer treatment are still controversial, researchers think that MNPs will play an important role in meeting health needs in the future. In this review, we present advances\rin in-vitro and in-vivo research for diagnosis and treatment, besides an overview of the basic technical principles of MNPs