Publication:
Prognostic Significance of Hemoglobin-To Cell Distribution Width Ratio in Patients With Metastatic Renal Cancer

Simple item page
dc.authorscopusid57202594040
dc.authorscopusid57208705587
dc.authorscopusid36702709300
dc.authorwosidYilmaz, Hatice/Aab-1397-2022
dc.authorwosidYilmaz, Ali/Aao-4203-2020
dc.contributor.authorYilmaz, Hatice
dc.contributor.authorYilmaz, Ali
dc.contributor.authorDemirag, Guzin
dc.contributor.authorIDYilmaz, Hatice/0000-0001-5341-5646
dc.date.accessioned2025-12-11T01:12:30Z
dc.date.issued2021
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Yilmaz, Hatice; Demirag, Guzin] Ondokuz Mayis Univ, Fac Med, Dept Med Oncol, Samsun, Turkey; [Yilmaz, Ali] Ataturk Univ, Fac Med, Dept Med Oncol, Erzurum, Turkeyen_US
dc.descriptionYilmaz, Hatice/0000-0001-5341-5646en_US
dc.description.abstractThe aim of the current research was to investigate the prognostic significance of pretreatment hemoglobin-to-red cell distribution width ratio (HRR) in patients with renal cell carcinoma (RCC). The neutrophil-to-lymphocyte ratio, systemic immune-inflammation index, lymphocyte-to-monocyte ratio (LMR) and HRR were analyzed retrospectively to assess their prognostic value using Kaplan-Meier curves and Cox regression analysis in 198 patients with RCC. High HRR (0.72) and high LMR (2.43) were found to be associated with longer progression-free survival and overall survival. A multivariate analysis identified International Metastatic Renal Cell Carcinoma Database Consortium prognostic score, tumor stage, node stage, LMR and HRR as independent prognostic factors for progression-free survival, as well as International Metastatic Renal Cell Carcinoma Database Consortium score, neutrophil-to-lymphocyte ratio and HRR for overall survival. HRR is a an independent prognostic parameter predicting the progression and survival of patients with RCC. Lay abstract Hemoglobin-to-red cell distribution width ratio (HRR) may be associated with lifespan in patients with cancer, as shown in previous studies of solid organ malignancy. The present study investigates the prognostic significance of pretreatment HRR in patients with renal cell carcinoma. A higher HRR was associated with longer survival in the present study, indicating the value of HRR as a predictor of survival and prognosis in renal cancer.en_US
dc.description.woscitationindexScience Citation Index Expanded
dc.identifier.doi10.2217/fon-2021-0040
dc.identifier.endpage3864en_US
dc.identifier.issn1479-6694
dc.identifier.issn1744-8301
dc.identifier.issue29en_US
dc.identifier.pmid34382414
dc.identifier.scopus2-s2.0-85116399204
dc.identifier.scopusqualityQ3
dc.identifier.startpage3853en_US
dc.identifier.urihttps://doi.org/10.2217/fon-2021-0040
dc.identifier.urihttps://hdl.handle.net/20.500.12712/42018
dc.identifier.volume17en_US
dc.identifier.wosWOS:000684263300001
dc.identifier.wosqualityQ3
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofFuture Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHemoglobinen_US
dc.subjectLymphocyteen_US
dc.subjectMonocyteen_US
dc.subjectPrognosisen_US
dc.subjectRed Cell Distribution Widthen_US
dc.subjectRenal Cell Carcinomaen_US
dc.subjectSurvivalen_US
dc.titlePrognostic Significance of Hemoglobin-To Cell Distribution Width Ratio in Patients With Metastatic Renal Canceren_US
dc.typeArticleen_US
dspace.entity.typePublication

Files

Collections

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu