Juvenile Myoclonic Epilepsy

Abstract

Juvenile Myoclonic Epilepsy (JME) is a genetically determined primary generalized epileptic syndrome. JME syndrome is characterized by myoclonic jerks often associated with generalized tonic clonic seizures and typical absence seizures. JME is a relatively benign form of idiopathic generalized epilepsy and typically occurs in adolescence. JME is often misdiagnosed despite its high prevalence, typical clinical and electroencephalography (EEG) findings. It usually responds well to treatment with valproic acid. The article reviews the clinical and electroencephalographic features of JME and ways to reduce diagnostic errors and to optimize clinical management.