Myocardial Perfusion Imaging: Pitfalls and Artifacts

Abstract

Myocardial perfusion scintigraphy has long been utilized as a non-invasive imaging modality for the clinical assessment of coronary artery disease. This technique involves the assessment of myocardial cell perfusion by evaluating images obtained following the injection of radiopharmaceuticals, allowing for the identification of ischemic or infarcted areas. Additionally, it provides the opportunity to assess parameters such as wall motion and thickening through images synchronized with electrocardiography. Due to the complex physiological processes reflected in the myocardium by this imaging technique, it encompasses a range of potential pitfalls and artifacts that could lead to misinterpretations, resulting in false-positive or false-negative evaluations. Therefore, it is imperative that the entire team involved in both the preparation of patients and the imaging process possesses knowledge to anticipate, preferably prevent, or rectify potential issues. This review aims to discuss pitfalls and artifacts that may arise at various stages of myocardial perfusion scintigraphy, potentially leading to misinterpretations of the examination. Furthermore, it provides insights into precautions that should be taken and potential solutions when possible. © 2024 Galenos Publishing House. All rights reserved.