Publication:
Evolution of an Extended Pathogenicity Motif in VP2 of Infectious Pancreatic Necrosis Virus Isolates From Farmed Rainbow Trout in Turkey

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dc.authorscopusid57189622256
dc.authorscopusid57193559726
dc.authorscopusid56496964200
dc.authorscopusid57219087229
dc.authorscopusid15022065800
dc.authorscopusid7004711811
dc.authorwosidKuruçay, Hanne/Jco-2237-2023
dc.authorwosidTamer, Cüneyt/Afh-9368-2022
dc.authorwosidWeidmann, Manfred/G-1817-2015
dc.authorwosidAlbayrak, Harun/Abc-7260-2020
dc.contributor.authorTamer, Cuneyt
dc.contributor.authorUlrich, Kristina
dc.contributor.authorDi Paola, Nicholas
dc.contributor.authorKurucay, Hanne Nur
dc.contributor.authorAlbayrak, Harun
dc.contributor.authorWeidmann, Manfred
dc.contributor.authorIDKurucay, Hanne Nur/0000-0001-5157-2090
dc.contributor.authorIDTamer, Cuneyt/0000-0003-3240-8425
dc.contributor.authorIDWeidmann, Manfred/0000-0002-7063-7491
dc.contributor.authorIDAlbayrak, Harun/0000-0002-4468-2790
dc.date.accessioned2025-12-11T01:31:23Z
dc.date.issued2024
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Tamer, Cuneyt; Kurucay, Hanne Nur; Albayrak, Harun] Ondokuz Mayis Univ, Fac Vet Med, Dept Virol, TR-55139 Samsun, Turkiye; [Ulrich, Kristina] Univ Stirling, Inst Aquaculture, Stirling FK9 4LA, Scotland; [Di Paola, Nicholas] US Army Med Res Inst Infect Dis, Ctr Genome Sci, Ft Detrick, Frederick, MD 21702 USA; [Weidmann, Manfred] Med Hsch Brandenburg Theodor Fontane, D-01968 Senftenberg, Germanyen_US
dc.descriptionKurucay, Hanne Nur/0000-0001-5157-2090; Tamer, Cuneyt/0000-0003-3240-8425; Weidmann, Manfred/0000-0002-7063-7491; Albayrak, Harun/0000-0002-4468-2790;en_US
dc.description.abstractInfectious pancreatic necrosis virus (IPNV) causes economic losses with a highly variable mortality rate worldwide, especially in rainbow trout. The virus has a double-stranded bi-partite RNA genome designated segment A and B. New complete genome sequences of nine rainbow trout isolates from Turkey were determined and subjected to phylogenetic analysis, identifying all as genotype 5 (serotype Sp). A time-dependent change in the extended pathogenicity motif of VP2 from P217T221A247 (PTA) to PTE P217T221E247 over a period of 10 years was identified. A wider analysis of 99 IPNV sequences from Turkey and Iran revealed the emergence of the motif PTE from 2007 to 2017, inducing significant morbidity in fry by 2013. In fact, displacement of the PTA motif, by the PTE motif in IPNV isolates appeared to be connected to a production peak of rainbow trout in 2013. An additional CAI analysis provided more evidence, indicating that rainbow trout culture in Turkey has an influence on the evolution of IPNV.en_US
dc.description.woscitationindexScience Citation Index Expanded
dc.identifier.doi10.3390/v16060994
dc.identifier.issn1999-4915
dc.identifier.issue6en_US
dc.identifier.pmid38932285
dc.identifier.scopus2-s2.0-85197188710
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3390/v16060994
dc.identifier.urihttps://hdl.handle.net/20.500.12712/44277
dc.identifier.volume16en_US
dc.identifier.wosWOS:001255743000001
dc.identifier.wosqualityQ2
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofViruses-Baselen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInfectious Pancreatic Necrosis Virusen_US
dc.subjectIPNVen_US
dc.subjectSp Serotypeen_US
dc.subjectVP2en_US
dc.subjectExtended Motifen_US
dc.titleEvolution of an Extended Pathogenicity Motif in VP2 of Infectious Pancreatic Necrosis Virus Isolates From Farmed Rainbow Trout in Turkeyen_US
dc.typeArticleen_US
dspace.entity.typePublication

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