The Interaction of Aspirin and Ascorbic Acid Absorption in Healthy Young Individuals

Abstract

Aspirin (acetylsalicyclic acid) and vitamin C (ascorbic acid) are commonly used two drugs. Metabolic importance of vitamin C has been risen due to understanding the function of vitamin C on metabolic pathway in human. To known how maintain serum and tissue levels in normal ranges is very crucial to avoid vitamin C deficiency. Therefore vitamin C and drug interaction, particulary for long term use, is very important to keep vitamin C in physiologic level. There have been some studies regarding the interaction of vitamin C and aspirin interaction indicating the inhibition of vitamin C absorption by aspirin. The present study, here, also reports inhibition of aspirin absorption by vitamin C.