A Case Report and Literature Review of Cutaneous Intravascular Large B-Cell Lymphoma Presenting Clinically as Panniculitis: A Difficult Diagnosis, but a Good Prognosis

Abstract

Intravascular large B-cell lymphoma is a rare, non-mass-forming, extranodal large B-cell lymphoma subtype characterized by the presence of tumor cells in the lumens of vessels. It is divided into two major types: classical and Asian. Patients presenting only with skin involvement are mostly female, at a younger age than classical intravascular large B-cell lymphoma patients, and have a better prognosis. Since the diagnosis of cases with isolated skin involvement is difficult, keeping this entity in mind, performing a careful microscopic examination, and applying new, effective treatment regimens will make it possible to achieve better clinical outcomes in these cases. (C) 2021 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.