Pentraxin-3 Level in Subarachnoid Haemorrhage: Is It a Prognostic Factor

Abstract

Objective: The current study was planned to investigate the relationship of serum level of pentraxine-3 with various clinical and neurological scales and scores.. Methods: The prospective case -control study was conducted at the Emergency Department of the Ondokuz Mayis University, Samsun, Turkey, from March 2013 to June 2014, and comprised subarachnoid haemorrhage patients and healthy. Pentraxine-3levels were measured from serum samples and compared with sub -groups of the various scales and scores used in the study. Data was analysed using SPSS 15. Results: Of the 77 subjects, 40(52%) were patients and 37(48%) were controls. Pentraxine-3levels in the cases were significantly higher than the controls (p<0.001). Among the cases, pentraxine-3level of the Glasgow Coma Scale sub -group was significantly different between the severe and mild categories (p=0.048). Likewise, pentraxine-3 levels were significantly different in terms of Fisher scale in patients with minor haemorrhage compared to those with massive haemorrhage (p=0.026). Also, pentraxine-3 levels were significantly higher in patients who died compared to those who fully recovered (p=0.042). Conclusion: There was found to be a relationship between pentraxine-3 level and the clinical severity of subarachnoid haemorrhage patients.