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The Changes in Lipid Peroxidation and GSH Levels in the Cerebellum of Rats Induced by Ethanol Consumption Are Prevented by Vitamin E

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dc.authorscopusid7003281190
dc.authorscopusid7006702494
dc.authorscopusid6602733768
dc.authorscopusid55909847400
dc.authorscopusid6602693377
dc.authorscopusid57197410463
dc.contributor.authorAǧar, E.
dc.contributor.authorDemir, S.
dc.contributor.authorAmanvermez, R.
dc.contributor.authorBoşnak, M.
dc.contributor.authorAyyildiz, M.
dc.contributor.authorÇelik, C.
dc.date.accessioned2025-12-11T02:01:25Z
dc.date.issued2000
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Aǧar] Erdal, Department of Physics, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Demir] Şerif, Department of Physics, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Amanvermez] Ramazan, Department of Biochemistry, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Boşnak] Mehmet, Department of Physics, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Ayyildiz] Mustafa, Department of Physics, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Çelik] Cemil, Department of Biochemistry, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractThe present study used male Wistar rats to investigate changes in glutathione (GSH) and lipid peroxidation (TBARS) in the cerebellum of 10%, 25%, 35% ethanol-consuming rats with or without vitamin E treatment when compared to the control group, the level of lipid peroxidation was increased 58.3%, 68.7%, 66.7% in rats consuming 10%, 25%, 35% ethanol, respectively. Ethanol decreased GSH levels in the cerebellum. This decrease was dose-dependent with 23.7%, 27.6%, 28% decreases in GSH in the cerebellum of rats consuming 10%, 25% or 35% ethanol, respectively. Vitamin E (100 mg/kg/day, i.p) treatment prevented the increase in the lipid peroxidation and decreases in cerebellum GSH levels of ethanol-consuming rats.en_US
dc.identifier.doi10.1002/1520-6769(200011/12)27:3<191
dc.identifier.endpage197en_US
dc.identifier.issn0893-6609
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-0034520362
dc.identifier.scopusqualityN/A
dc.identifier.startpage191en_US
dc.identifier.urihttps://doi.org/10.1002/1520-6769(200011/12)27:3<191
dc.identifier.urihttps://hdl.handle.net/20.500.12712/47589
dc.identifier.volume27en_US
dc.identifier.wosqualityN/A
dc.language.isoenen_US
dc.relation.ispartofNeuroscience Research Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCerebellumen_US
dc.subjectGlutathioneen_US
dc.subjectLipid Peroxidationen_US
dc.subjectVitamin Een_US
dc.titleThe Changes in Lipid Peroxidation and GSH Levels in the Cerebellum of Rats Induced by Ethanol Consumption Are Prevented by Vitamin Een_US
dc.typeArticleen_US
dspace.entity.typePublication

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