Coincidence of an Insular Thyroid Carsinoma and Chronic Lymphocytic Leukemia; A Case Report

Abstract

Chronic lymphocytic leukemia (CLL) Is a hematologlical malignancy characterized with proliferation and accumulation of lymphocytes of mature appearance in blood, liver, bone marrow, lymph nodes and other tissues. Second malignancies occur with an increased frequency in CLL. The most frequent of these are large cell lymphoma, known as Richter's syndrome and Hodgkin's disease among hematological second malignancies, lung and skin cancers among solid tumors. The defect in humoral and cellular functions may be the underlying mechanism of increased tendency towards infections and second malignancies in CLL patients. Here we report a coexistence of insular thyroid carcinoma (ITC) and B-CLL in the same patient. The occurrence of both CLL and insular thyroid carcinoma described because of the rarity of the coexistence of these two disorders in the same patient.