Comparison of NSAID Therapy Alone Versus Combined NSAID and Home Exercise Therapy in Patients with Temporomandibular Joint Osteoarthritis and Arthralgia

Abstract

Objective: To compare nonsteroidal anti-inflammatory drug (NSAID) therapy alone with NSAID plus home exercise in temporomandibular joint (TMJ) osteoarthritis and arthralgia. Methods: Sixty patients received Tenoxicam 20 mg/day alone (Group 1) or with home exercise (Group 2). Outcomes were mandibular range of motion (RoM), pain (VAS), and TMD-related quality of life (TMD-QoL). Results: Group 2 showed greater MMO increase (+3.9 mm, p <.005) than Group 1 (+0.7 mm, p >.05). VAS decreased similarly in both groups (p <.005; between-group p >.05). TMD-QoL improved more in Group 2 (p <.05). Conclusion: NSAID plus exercise yields superior functional and QoL benefits versus NSAID alone, with comparable pain relief. © 2025 Taylor & Francis Group, LLC.