Publication:
Hemostatic Efficacy of Ankaferd Blood Stopper® in a Swine Bleeding Model

dc.authorscopusid6602644694
dc.authorscopusid59263605100
dc.authorscopusid8620567200
dc.authorscopusid10143610800
dc.authorscopusid57203104682
dc.authorscopusid24437143400
dc.authorscopusid56208176300
dc.contributor.authorBılgılı, H.
dc.contributor.authorKoşar, A.
dc.contributor.authorKurt, M.
dc.contributor.authorÖnal, I.K.
dc.contributor.authorGöker, H.
dc.contributor.authorÇaptug, O.
dc.contributor.authorShorbagi, A.
dc.date.accessioned2020-06-21T15:08:35Z
dc.date.available2020-06-21T15:08:35Z
dc.date.issued2009
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Bılgılı] Hasan, Department of Surgery, Ankara Üniversitesi, Ankara, Turkey; [Koşar] Ali Morad, Department of Hematology, Fatih Üniversitesi Tip Fakültesi ve Hastanesi, Ankara, Turkey; [Kurt] Mevlut, Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey, Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey; [Önal] Ibrahim Koral, Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey; [Göker] Hakan, Departments of Hematology, Ankara, Turkey; [Çaptug] Ozge, Department of Surgery, Ankara Üniversitesi, Ankara, Turkey; [Shorbagi] Ali Ibrahim, Department of Gastroenterology, Hacettepe Üniversitesi, Ankara, Turkey; [Turgut] Mehmet, Department of Hematology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Kekilli] Murat, Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey; [Kurt] Ozlem Kar, Department of Chest Diseases, Children's Education and Research Hospital, Ankara, Turkey; [Kirazli] Şerafettin, Departments of Hematology, Ankara, Turkey; [Aksu] Salih, Departments of Hematology, Ankara, Turkey; [Haznedarogˇlu] Ibrahim Celalettin, Departments of Hematology, Ankara, Turkeyen_US
dc.description.abstractObjective: The purpose of this study was to show the hemostatic effect of spray, solution and tampon forms of Ankaferd Blood Stopper® (ABS), a unique medicinal plant extract historically used as a hemostatic agent in Turkish folklore medicine, in a porcine bleeding model. Materials and Methods: Two 1-year-old pigs were used as bleeding models for superficial and deep skin lacerations, grade II liver and spleen injuries, grade II saphenous vein injury and grade IV saphenous artery injury. Spray, solution or tampon forms of ABS were applied after continuing bleeding was confirmed. The primary outcome was time to hemostasis. Volume of blood loss was not measured. The pigs were euthanized at the end of the experiment. Results: Spray or direct application of ABS solution resulted in instant control of bleeding in superficial and deep skin lacerations as well as puncture wounds of the liver. A 40-second application of ABS tampon was sufficient to stop bleeding of skin lacerations, while 1.5- and 3.5-min applications were used to control hemorrhage from the saphenous vein and artery, respectively. No rebleeding was observed once hemostasis was achieved. However, repeated applications of ABS solution and tampon were only temporarily effective in the hemostasis of spleen injury. Conclusions: The data showed that ABS was an effective hemostatic agent for superficial and deep skin lacerations and minor/moderate trauma injuries in a porcine bleeding model. Copyright © 2009 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000204344
dc.identifier.endpage169en_US
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue3en_US
dc.identifier.pmid19349716
dc.identifier.scopus2-s2.0-64349105181
dc.identifier.scopusqualityQ1
dc.identifier.startpage165en_US
dc.identifier.urihttps://doi.org/10.1159/000204344
dc.identifier.urihttps://hdl.handle.net/20.500.12712/18991
dc.identifier.volume18en_US
dc.identifier.wosWOS:000265114700001
dc.identifier.wosqualityQ2
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.journalMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnkaferd Blood Stopper®en_US
dc.subjectHemorrhageen_US
dc.subjectHemostasisen_US
dc.subjectPorcine Animal Modelen_US
dc.titleHemostatic Efficacy of Ankaferd Blood Stopper® in a Swine Bleeding Modelen_US
dc.typeArticleen_US
dspace.entity.typePublication

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