Publication:
Overexpression of bcl-2 in Lymphocytes of Psoriatic Skin

dc.contributor.authorYildiz, L
dc.contributor.authorBaris, S
dc.contributor.authorSenturk, N
dc.contributor.authorKandemir, B
dc.date.accessioned2020-06-21T15:43:57Z
dc.date.available2020-06-21T15:43:57Z
dc.date.issued2003
dc.departmentOMÜen_US
dc.department-tempOndokuz Mayis Univ, Tip Fak Patoloji Anabilim Dali, Sch Med, Dept Pathol, TR-55139 Kurupelit, Turkey -- Ondokuz Mayis Univ, Tip Fak Patoloji Anabilim Dali, Sch Med, Dept Dermatol, TR-55139 Kurupelit, Turkey --en_US
dc.description.abstractBcl-2 overexpression in lymphocytes play an important part in immunological and inflammatory diseases. In the present study, we investigated the bcl-2 expression in dermal lymphocytes of psoriatic skin biopsy samples. From the archives of the Department of Pathology, Ondokuz Mayis University Medical School (Samsun, Turkey), tissue sections belonging to 28 psoriasis cases and 10 chronic non-specific inflammatory skin disease cases were immunohistochemically stained by bcl-2. Positive staining was semiquantitatively graded from 1 + to 4 +. Of the 28 psoriasis cases 20 were found to express bcl-2. Our data suggest that bcl-2-mediated inflammation plays a part in the pathogenesis and recurrent character of psoriasis.en_US
dc.identifier.doi10.1046/j.1468-3083.2003.00805.x
dc.identifier.endpage540en_US
dc.identifier.issn0926-9959
dc.identifier.issn1468-3083
dc.identifier.issue5en_US
dc.identifier.pmid12941088
dc.identifier.startpage538en_US
dc.identifier.urihttps://doi.org/10.1046/j.1468-3083.2003.00805.x
dc.identifier.urihttps://hdl.handle.net/20.500.12712/21746
dc.identifier.volume17en_US
dc.identifier.wosWOS:000188944300008
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalJournal of the European Academy of Dermatology and Venereologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBcl-2en_US
dc.subjectPsoriasisen_US
dc.titleOverexpression of bcl-2 in Lymphocytes of Psoriatic Skinen_US
dc.typeArticleen_US
dspace.entity.typePublication

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