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Protective Effect of Centranthus Longiflorus Subsp, Longiflorus in Glutamate Induced Neurotoxicity

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dc.authorscopusid6701489901
dc.authorscopusid7003758109
dc.authorscopusid6508093438
dc.authorscopusid57190524537
dc.authorscopusid36118867300
dc.authorscopusid6701357081
dc.contributor.authorBüyükokuroģlu, M.E.
dc.contributor.authorGepdiremen, A.
dc.contributor.authorHalıcı, Z.
dc.contributor.authorDuzenli, S.
dc.contributor.authorGuyenalp, Z.
dc.contributor.authorDemirezer, L.O.
dc.date.accessioned2025-12-10T21:49:17Z
dc.date.issued2010
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Büyükokuroģlu] Mehmet Emin, Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey,; [Gepdíremen] Akçahan, Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey, Faculty of Medicine, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey; [Halıcı] Zekai, Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey, Department of Pharmacology, Faculty of Medicine, Samsun, Edirne, Turkey; [Duz̈enli] Selma, Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey, , Faculty of Medicine, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Guyenalp] Z., Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey, Department of Pharmacognosy, Atatürk Üniversitesi, Erzurum, Erzurum, Turkey; [Demirezer] Lütfiye Ömür, Department of Pharmacology, Afyon Kocatepe Üniversitesi, Afyonkarahisar, Afyonkarahisar, Turkey, Department of Pharmacognosy, Hacettepe Üniversitesi, Ankara, Turkeyen_US
dc.description.abstractIn the present study, neuroprotective effect of the aquoeus extract of Centranthus longiflorus subsp. Iongiflorus in glutamate induced toxicity in rat pups cerebellar granular cell culture was investigated. The extract at doses of 50 μg.ml-1, 100 μ.g.ml-1 250 μg.ml-1, 500 μg.ml-1 and 1000 μg.ml-1 was applied to culture flasks. At all doses the extract significantly blocked glutamate - induced neurotoxicity, with the most effective dose being 500 μg.ml-1. As a result, Centranthus longiflorus subsp. longiflorus protected the neurons against glutamate toxicity.en_US
dc.identifier.endpage246en_US
dc.identifier.issn0019-6479
dc.identifier.issn0974-9365
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-77950247284
dc.identifier.scopusqualityQ4
dc.identifier.startpage244en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12712/34878
dc.identifier.volume87en_US
dc.language.isoenen_US
dc.relation.ispartofIndian Veterinary Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleProtective Effect of Centranthus Longiflorus Subsp, Longiflorus in Glutamate Induced Neurotoxicityen_US
dc.typeArticleen_US
dspace.entity.typePublication

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