Publication: Morbidity and Mortality After Anaesthesia in Early Life: Results of the European Prospective Multicentre Observational Study, Neonate and Children Audit of Anaesthesia Practice in Europe (NECTARINE)
| dc.authorscopusid | 9738577700 | |
| dc.authorscopusid | 7004815723 | |
| dc.authorscopusid | 36629447100 | |
| dc.authorscopusid | 26643442300 | |
| dc.authorscopusid | 21933510000 | |
| dc.authorscopusid | 57193987445 | |
| dc.authorscopusid | 25961015400 | |
| dc.contributor.author | Disma, N. | |
| dc.contributor.author | Veyckemans, F. | |
| dc.contributor.author | Virág, K. | |
| dc.contributor.author | Hansen, T.G. | |
| dc.contributor.author | Becke-Jakob, K. | |
| dc.contributor.author | Harlet, P. | |
| dc.contributor.author | Vutskits, L. | |
| dc.date.accessioned | 2025-12-11T00:28:14Z | |
| dc.date.issued | 2021 | |
| dc.department | Ondokuz Mayıs Üniversitesi | en_US |
| dc.department-temp | [Disma] Nicola Massimo, Department of Anaesthesia, Istituto Giannina Gaslini, Genoa, Italy, Istituto Giannina Gaslini, Genoa, Italy; [Veyckemans] Francis A., Département d'Anaesthésie-Réanimation pédiatrique, CHU Lille, Lille, Hauts-de-France, France, Cliniques Universitaires Saint-Luc, Brussels, BRU, Belgium; [Virág] Katalin, Department of Medical Physics and Informatics, Szegedi Tudományegyetem (SZTE), Szeged, Hungary; [Hansen] Tom Giedsing, Odense Universitetshospital, Odense, Syddanmark, Denmark; [Becke-Jakob] Karin, Department of Anaesthesia and Intensive Care, Cnopf Children's Hospital, Nurnberg, Germany, Cnopf Childrens Hospital, Germany; [Harlet] Pierre, Department of Research, European Society of Anaesthesiology, Brussels, Belgium; [Vutskits] Laszlo, Department of Anesthesiology, Hôpitaux Universitaires de Genève, Geneva, GE, Switzerland, Université de Genève, Geneva, Switzerland, Geneva Children's Hospital, Geneva, GE, Switzerland; [Walker] Suellen M., Department of Anaesthesia and Pain Management, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom; [de Graaff] J. C., Department of Anesthesiology, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Zielińska] Marzena, Department of Paediatric Anaesthesiology and Intensive Care, Wroclaw Medical University, Wroclaw, DS, Poland, Wroclaw Medical University, Wroclaw, DS, Poland; [Simić] Dušica M., Department of Pediatric Anesthesia and Intensive Care, University Children's Hospital, Belgrade, Belgrade, Serbia, University Children's Hospital, Belgrade, Belgrade, Serbia; [Engelhardt] Thomas E., Department of Anaesthesia, Centre Universitaire de Santé McGill, Hôpital de Montreal Pour Enfants, Montreal, QC, Canada; [Habre] Walid N., Department of Anesthesiology, Hôpitaux Universitaires de Genève, Geneva, GE, Switzerland, Université de Genève, Geneva, Switzerland, Geneva Children's Hospital, Geneva, GE, Switzerland; [Breschan] Christian, Klinikum Klagenfurt, Klagenfurt, Austria; [Likar] Rudolf, Klinikum Klagenfurt, Klagenfurt, Austria; [Platzer] Manuela, Klinikum Klagenfurt, Klagenfurt, Austria; [Edelman] Isole, Medizinische Universität Graz, Graz, Styria, Austria; [Eger] Johanes, Medizinische Universität Graz, Graz, Styria, Austria; [Heschl] Stefan, Medizinische Universität Graz, Graz, Styria, Austria; [Messerer] Brigitte, Medizinische Universität Graz, Graz, Styria, Austria; [Vittinghof] Maria, Medizinische Universität Graz, Graz, Styria, Austria; [Kroess] Ruth, Universität Innsbruck, Innsbruck, Tyrol, Austria; [Stichlberger] Martina, Universität Innsbruck, Innsbruck, Tyrol, Austria; [Kahn] David A., Cliniques Universitaires Saint-Luc, Brussels, BRU, Belgium; [Pirotte] Thierry, Cliniques Universitaires Saint-Luc, Brussels, BRU, Belgium; [Pregardien] Caroline, Cliniques Universitaires Saint-Luc, Brussels, BRU, Belgium; [Stevens] France, Grand Hôpital de Charleroi, Charleroi, Belgium; [Berghmans] Johan M., Queen Paola Children's Hospital, Antwerpen, Belgium; [Bauters] Annemie, Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [de Baerdemaeker] Luc E.C., Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [de Hert] Stefan G., Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [Lapage] K., Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [Parashchanka] Aliaksandra, Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [van Limmen] Jurgen G.M., Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [Wyffels] Piet A.H., Universitair Ziekenhuis Gent, Ghent, VOV, Belgium; [Lauweryns] Julie, KU Leuven– University Hospital Leuven, Leuven, Vlaams-Brabant, Belgium; [Najafi] Nadia, Universitair Ziekenhuis Brussel, Jette, Belgium; [Vundelinckx] Joris, Ziekenhuis Oost-Limburg, Genk, VLI, Belgium; [Butković] Diana, Childern's Hospital Zagreb, Zagreb, Croatia; [Soric] Ivana Kerovec, Childern's Hospital Zagreb, Zagreb, Croatia; [Kralik] Sandra, Childern's Hospital Zagreb, Zagreb, Croatia; [Markić] Ana, Childern's Hospital Zagreb, Zagreb, Croatia; [Ažman] Josip, Klinički Bolnički Centar Rijeka, Rijeka, Croatia; [Markić] Joško, Klinički Bolnički Centar Split, Split, Split-Dalmatia, Croatia; [Pupačić] Daniela, Klinički Bolnički Centar Split, Split, Split-Dalmatia, Croatia; [Frelich] Michal, Faculty Hospital Ostrava, Ostrava, Czech Republic; [Reimer] Petr, Faculty Hospital Ostrava, Ostrava, Czech Republic; [Urbanec] René, Faculty Hospital Ostrava, Ostrava, Czech Republic; [Cajkova] Petra, Fakultní Nemocnice v Motole, Prague, Czech Republic; [Mixa] Vladimír, Fakultní Nemocnice v Motole, Prague, Czech Republic; [Sedláčková] Yvona, Fakultni Nemocnice Brno, Brno, South Moravian Region, Czech Republic; [Knoppova] Lenka, Fakultni Nemocnice Brno, Brno, South Moravian Region, Czech Republic; [Zlamalova (nee Květoňova)] Alena, Fakultni Nemocnice Brno, Brno, South Moravian Region, Czech Republic; [Vavřina] Martin, Fakultni Nemocnice Brno, Brno, South Moravian Region, Czech Republic; [Zurek] Jiri, Fakultni Nemocnice Brno, Brno, South Moravian Region, Czech Republic; [Afshari] Arash, Department of Anesthesiology, Københavns Universitet, Copenhagen, Hovedstaden, Denmark; [Bille] Anders Bastholm, Department of Anesthesiology, Københavns Universitet, Copenhagen, Hovedstaden, Denmark; [Ellekvist] Marguerite B., Department of Anesthesiology, Københavns Universitet, Copenhagen, Hovedstaden, Denmark; [Ilmoja] Mari Liis, Tallinn Children's Hospital, Tallinn, Harjumaa, Estonia; [Moor] Reet, Tallinn Children's Hospital, Tallinn, Harjumaa, Estonia; [Kikas] Reet, Tartu Ülikooli Kliinikum, Tartu, Tartumaa, Estonia; [Väli] Merle, Tartu Ülikooli Kliinikum, Tartu, Tartumaa, Estonia; [Kallio] Kariantti, Helsinki University Hospital, Helsinki, Finland; [Reponen] Elisa, Helsinki University Hospital, Helsinki, Finland; [Suominen] Pertti K., Helsinki University Hospital, Helsinki, Finland; [Suvanto] Sami, Helsinki University Hospital, Helsinki, Finland; [Vähätalo] Raisa, Helsinki University Hospital, Helsinki, Finland; [Kokki] Hannu J., Kuopio University Hospital, Kuopio, Finland; [Kokki] Merja, Kuopio University Hospital, Kuopio, Finland; [Harju] Jarkko A., University Hospital of Tampere, Tampere, Pirkanmaa, Finland; [Kokkonen] Miia, University Hospital of Tampere, Tampere, Pirkanmaa, Finland; [Vieri] Jenni, University Hospital of Tampere, Tampere, Pirkanmaa, Finland; [Manner] Tuula E., Turun Yliopistollinen Keskussairaala, Turku, Southwest Finland, Finland; [Amory] Catherine, American Memorial Hospital, Reims, Grand Est, France; [Ludot] Hugues, American Memorial Hospital, Reims, Grand Est, France; [Bert] Dina, CHU Lille, Lille, Hauts-de-France, France; [Godart] Juliette, CHU Lille, Lille, Hauts-de-France, France; [Laffargue] Anne, CHU Lille, Lille, Hauts-de-France, France; [Dupont] Hervé, CHU Amiens Picardie, Amiens, France; [Urbina] Benjamin, CHU Amiens Picardie, Amiens, France; [Baujard] Catherine,; [Roulleau] Philippe,; [Staiti] Giuseppe,; [Bordes] Maryline, Centre Hospitalier Universitaire de Bordeaux, Talence, Nouvelle-Aquitaine, France; [Gaulain] Karine Nouette, Centre Hospitalier Universitaire de Bordeaux, Talence, Nouvelle-Aquitaine, France; [Hamonic] Yann, Centre Hospitalier Universitaire de Bordeaux, Talence, Nouvelle-Aquitaine, France; [Semjen] François, Centre Hospitalier Universitaire de Bordeaux, Talence, Nouvelle-Aquitaine, France; [Jacqmarcq] Olivier, CHU de Nantes, Nantes, Pays-de-la-Loire, France; [Lejus-Bourdeau] Caroline, CHU de Nantes, Nantes, Pays-de-la-Loire, France; [Magne] Cécile, CHU de Nantes, Nantes, Pays-de-la-Loire, France; [Petry] Lea, CHU de Nancy, Nancy, France; [Ros] Lilica, CHU de Nancy, Nancy, France; [Zang] Aurélien, CHU de Nancy, Nancy, France; [Bennis] Mehdi, CHU de Toulouse, Toulouse, Occitanie, France; [Coustets] Bernard, CHU de Toulouse, Toulouse, Occitanie, France; [Fesseau] Rose, CHU de Toulouse, Toulouse, Occitanie, France; [Constant] Isabelle, Hôpital Armand-Trousseau, Paris, Ile-de-France, France; [Khalil] Eliane, Hôpital Armand-Trousseau, Paris, Ile-de-France, France; [Sabourdin] Nada, Hôpital Armand-Trousseau, Paris, Ile-de-France, France; [Audren] Noémie, Hôpital Couple-Enfant, Centre Hospitalier Universitaire de Grenoble, Grenoble, Auvergne-Rhone-Alpes, France; [Descarpentries] Thomas, Hôpital Couple-Enfant, Centre Hospitalier Universitaire de Grenoble, Grenoble, Auvergne-Rhone-Alpes, France; [Fabre] Fanny, Hôpital Couple-Enfant, Centre Hospitalier Universitaire de Grenoble, Grenoble, Auvergne-Rhone-Alpes, France; [Legrand] Aurélien, Hôpital Couple-Enfant, Centre Hospitalier Universitaire de Grenoble, Grenoble, Auvergne-Rhone-Alpes, France; [Druot] Emilie, Hopital Universitaire Necker-Enfants Malades, France; [Orliaguet] G. A., Hopital Universitaire Necker-Enfants Malades, France; [Sabau] Lucie, Hopital Universitaire Necker-Enfants Malades, France; [Uhrig] Lynn, Hopital Universitaire Necker-Enfants Malades, France; [de la Brière] François, Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Jonckheer] Karin, Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Mission] Jean Paul, Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Scordo] Lucia, Centre Hospitalier Universitaire de Nice, Nice, Provence-Alpes-Cote d'Azur, France; [Couchepin] Caroline, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [Dadure] Christophe, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [de la Arena] Pablo, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [Hertz] Laurent, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [Pirat] Philippe, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [Sola] Chrystelle, Centre Hospitalier Universitaire de Montpellier, Montpellier, Occitanie, France; [Bellon] Myriam, Robert Debré University Hospital, France; [Dahmani] Souhayl, Robert Debré University Hospital, France; [Julien-Marsollier] Florence, Robert Debré University Hospital, France; [Michelet] Daphné, Robert Debré University Hospital, France; [Depret-Donatien] Veronique, CHU de Caen Normandie, Caen, Normandie, France; [Lesage] Anne, CHU de Caen Normandie, Caen, Normandie, France; [Kaufmann] Jost, Children's Hospital Cologne, Koln, Germany; [Laschat] Michael, Children's Hospital Cologne, Koln, Germany; [Wappler] Frank, Children's Hospital Cologne, Koln, Germany; [Brunner] Lena, Cnopf Childrens Hospital, Germany; [Oppenrieder] Karin, Cnopf Childrens Hospital, Germany; [Badelt] Gregor, Klinik St. Hedwig, Regensburg, Germany; [Hochmuth] Karin, Klinik St. Hedwig, Regensburg, Germany; [Koller] Bernhard, Klinik St. Hedwig, Regensburg, Germany; [Reil] Anita, Klinik St. Hedwig, Regensburg, Germany; [Richter] Sebastian, Klinik St. Hedwig, Regensburg, Germany; [Fischer] Thomas, Klinikum Kassel GmbH, Kassel, Hessen, Germany; [Diers] Anja, Universität Oldenburg, Oldenburg, Niedersachsen, Germany; [Schorer] Clemens, Universität Oldenburg, Oldenburg, Niedersachsen, Germany; [Weyland] Andreas, Universität Oldenburg, Oldenburg, Niedersachsen, Germany; [Cohausz] Ruth, Klinikum Stuttgart Olgahospital, Stuttgart, Baden-Wurttemberg, Germany; [Kretz] Franz Josef, Klinikum Stuttgart Olgahospital, Stuttgart, Baden-Wurttemberg, Germany; [Loffler] Michaela, Klinikum Stuttgart Olgahospital, Stuttgart, Baden-Wurttemberg, Germany; [Wilbs] Markus, Klinikum Stuttgart Olgahospital, Stuttgart, Baden-Wurttemberg, Germany; [Höhne] Claudia, Universitaetsklinikum Leipzig, Leipzig, Germany; [Ulrici] Johanna, Universitaetsklinikum Leipzig, Leipzig, Germany; [Goeters] Christiane, Universitätsklinikum Münster, Munster, Niedersachsen, Germany; [Flinspach] Armin Niklas, Universitätsklinikum Frankfurt, Frankfurt am Main, Hessen, Germany; [Klages] Matthias, Universitätsklinikum Frankfurt, Frankfurt am Main, Hessen, Germany; [Lindau] Simone, Universitätsklinikum Frankfurt, Frankfurt am Main, Hessen, Germany; [Messroghli] Leila, Universitätsklinikum Frankfurt, Frankfurt am Main, Hessen, Germany; [Zacharowski] Kai D., Universitätsklinikum Frankfurt, Frankfurt am Main, Hessen, Germany; [Eisner] Christoph, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Mueller] Thomas, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Richter] Daniel, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Schafer] Melanie, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Weigand] Markus Alexander, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Weiterer] Sebastian, Universitätsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, Germany; [Ochsenreiter] Miriam, Universitätsklinikum Mannheim, Mannheim, Baden-Wurttemberg, Germany; [Schöler] Michael, Universitätsklinikum Mannheim, Mannheim, Baden-Wurttemberg, Germany; [Terboven] Tom, Universitätsklinikum Mannheim, Mannheim, Baden-Wurttemberg, Germany; [Eggemann] Isabel, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Haussmann] Sascha, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Leister] Nicolas, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Menzel] Christoph, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Trieschmann] Uwe, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Yücetepe] Sirin, Uniklinik Köln, Koln, Nordrhein-Westfalen, Germany; [Keilig] Susanna, Julius-Maximilians-Universität Würzburg, Wurzburg, Bayern, Germany; [Kranke] Peter R., Julius-Maximilians-Universität Würzburg, Wurzburg, Bayern, Germany; [Jelting] Yvonne, Julius-Maximilians-Universität Würzburg, Wurzburg, Bayern, Germany; [Baehner] Torsten, Universität Bonn, Bonn, Nordrhein-Westfalen, Germany; [Ellerkmann] Richard Klaus, Universität Bonn, Bonn, Nordrhein-Westfalen, Germany; [Ghamari] Shahab, Universität Bonn, Bonn, Nordrhein-Westfalen, Germany; [Neumann] Claudia, Universität Bonn, Bonn, Nordrhein-Westfalen, Germany; [Soehle] Martin, Universität Bonn, Bonn, Nordrhein-Westfalen, Germany; [Chloropoulou] Pelagia Paraskevi, Democritus University of Thrace, Komotini, Eastern Macedonia and Thrace, Greece; [Ntritsou] Vagia, G. Gennimatas General Hospital, Athens, Greece; [Papagiannopoulou] Pinelopi, G. Gennimatas General Hospital, Athens, Greece; [Garini] Eleana, General Pediatric Hospital “Agia Sophia”, Greece; [Karafotia] Afroditi, General Pediatric Hospital “Agia Sophia”, Greece; [Mammi] Panagoula, General Pediatric Hospital “Agia Sophia”, Greece; [Bali] Evangelia, Hippokration General Hospital of Thessaloniki, Thessaloniki, Central Macedonia, Greece; [Iordanidou] Despoina, Hippokration General Hospital of Thessaloniki, Thessaloniki, Central Macedonia, Greece; [Malisiova] Anna, P. & A. Kyriakou Children’s Hospital, Greece; [Polyzoi] Artemis, P. & A. Kyriakou Children’s Hospital, Greece; [Tsiotou] Adelais G.H., P. & A. Kyriakou Children’s Hospital, Greece; [Sápi] Erzsébet, Hungarian Institute of Cardiology, Budapest, Hungary; [Székely] Edgár A., Hungarian Institute of Cardiology, Budapest, Hungary; [Kósik] Nándor, Heim Pal National Pediatric Institute, Hungary; [Maráczi] Veronika, Heim Pal National Pediatric Institute, Hungary; [Schnur] Janos, Heim Pal National Pediatric Institute, Hungary; [Csillag] Judit, Semmelweis Egyetem, Budapest, Hungary; [Gál] János, Semmelweis Egyetem, Budapest, Hungary; [Göbl] Gergely, Semmelweis Egyetem, Budapest, Hungary; [Hauser] Balázs, Semmelweis Egyetem, Budapest, Hungary; [Petróczy] András, Semmelweis Egyetem, Budapest, Hungary; [Tövisházi] Gyula, Semmelweis Egyetem, Budapest, Hungary; [Blain] Stuart, Children's Health Ireland at Crumlin, Dublin, Ireland; [Gallagher] Sarah, Children's Health Ireland at Crumlin, Dublin, Ireland; [Harte] Sinead, Children's Health Ireland at Crumlin, Dublin, Ireland; [Jackson] Mandy, Children's Health Ireland at Crumlin, Dublin, Ireland; [Meehan] Emma, Children's Health Ireland at Crumlin, Dublin, Ireland; [Nawoor] Zeenat, Children's Health Ireland at Crumlin, Dublin, Ireland; [O'Hare] Brendan P., Children's Health Ireland at Crumlin, Dublin, Ireland; [Ross] Mark, Children's Health Ireland at Crumlin, Dublin, Ireland; [Lerro] Daniela, Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon, Naples, NA, Italy; [Astuto] Marinella, Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco", Catania, CT, Italy; [Grasso] Chiara, Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco", Catania, CT, Italy; [Scalisi] Rita, Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco", Catania, CT, Italy; [Frasacco] Giulia, Azienda Ospedaliero-Universitaria Meyer, Florence, FI, Italy; [Lenares] Elena, Azienda Ospedaliero-Universitaria Meyer, Florence, FI, Italy; [Leone] Roberto, Azienda Ospedaliero-Universitaria Meyer, Florence, FI, Italy; [Grazzini] Maurizia, Azienda Ospedale Università Padova, Padua, PD, Italy; [Minardi] Carmelo, Azienda Ospedale Università Padova, Padua, PD, Italy; [Zadra] Nicola, Azienda Ospedale Università Padova, Padua, PD, Italy; [Cinnella] Gilda, Azienda Ospedaliero-Universitaria - Ospedali Riuniti di Foggia, Foggia, Italy; [Cotoia] Antonella, Azienda Ospedaliero-Universitaria - Ospedali Riuniti di Foggia, Foggia, Italy; [Galante] Dario, Azienda Ospedaliero-Universitaria - Ospedali Riuniti di Foggia, Foggia, Italy; [de Lorenzo] Brita, Azienda Ospedaliero Universitaria Pisana, Pisa, PI, Italy; [Kuppers] Beate, Azienda Ospedaliero Universitaria Pisana, Pisa, PI, Italy; [Bottazzi] Giulia, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, BO, Italy; [Caramelli] Fabio, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, BO, Italy; [Mondardini] Maria Cristina, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, BO, Italy; [Rossetti] E., IRCCS Ospedale Pediatrico Bambino Gesù, Rome, RM, Italy; [Picardo] Sergio Giuseppe, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, RM, Italy; [Vittori] Alessandro, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, RM, Italy; [Camporesi] Anna, Children Hospital Vittore Buzzi, Italy; [Wolfler] Andrea, Children Hospital Vittore Buzzi, Italy; [Calderini] Edoardo, Ospedale Maggiore, Bologna, Emilia-Romagna, Italy; [Colantonio] Laura Brigitta, Ospedale Maggiore, Bologna, Emilia-Romagna, Italy; [Finamore] Simona Anna, Ospedale Maggiore, Bologna, Emilia-Romagna, Italy; [Porro] Giuliana Anna, Ospedale Maggiore, Bologna, Emilia-Romagna, Italy; [Bonfiglio] Rachele, Istituto Giannina Gaslini, Genoa, Italy; [Kotzeva] Svetlana, Istituto Giannina Gaslini, Genoa, Italy; [Mameli] Leila, Istituto Giannina Gaslini, Genoa, Italy; [Mattioli] G., Istituto Giannina Gaslini, Genoa, Italy; [Micalizzi] Camilla, Istituto Giannina Gaslini, Genoa, Italy; [Montaguti] Alessia, Istituto Giannina Gaslini, Genoa, Italy; [Pistorio] Angela, Istituto Giannina Gaslini, Genoa, Italy; [Zanaboni] Clelia, Istituto Giannina Gaslini, Genoa, Italy; [Guddo] Anna M., Ospedale dei bambini Di Cristina, Italy; [Neba] Gerald Rogan, Ospedale G. Salesi, Italy; [Favarato] Moreno, Ospedale Papa Giovanni XXIII, Italy; [Locatelli] Bruno Guido, Ospedale Papa Giovanni XXIII, Italy; [Maffioletti] Micol, Ospedale Papa Giovanni XXIII, Italy; [Sonzogni] Valter, Ospedale Papa Giovanni XXIII, Italy; [Garra] Rossella, Università Cattolica del Sacro Cuore, Campus di Roma, Rome, Lazio, Italy; [Sammartino] Maria, Università Cattolica del Sacro Cuore, Campus di Roma, Rome, Lazio, Italy; [Sbaraglia] Fabio, Università Cattolica del Sacro Cuore, Campus di Roma, Rome, Lazio, Italy; [Cortegiani] Andrea, Università degli Studi di Palermo, Palermo, PA, Italy; [Moscarelli] Alessandra, Università degli Studi di Palermo, Palermo, PA, Italy; [Attanasi] Elena, Analgesia and Intensive Care, kraliSection of Anesthesiology, Italy; [Tesoro] Simonetta, Analgesia and Intensive Care, kraliSection of Anesthesiology, Italy; [Agapiti] Cristina, Spedali Civili Di Brescia, Brescia, BS, Italy; [Pinzoni] Francesca, Spedali Civili Di Brescia, Brescia, BS, Italy; [Vezzoli] Cesare, Spedali Civili Di Brescia, Brescia, BS, Italy; [Bilotta] Federico F., Sapienza Università di Roma, Rome, RM, Italy; [Bārzdiņa] Arta, Children Clinical University Hospital, Latvia; [Straume] Zane, Children Clinical University Hospital, Latvia; [Zundane] Anda, Children Clinical University Hospital, Latvia; [Lukosiene] Laura, Lietuvos Sveikatos Mokslų Universitetas, Kaunas, Kaunas, Lithuania; [Maraulaite] Irena, Lietuvos Sveikatos Mokslų Universitetas, Kaunas, Kaunas, Lithuania; [Razlevice] Ilona, Lietuvos Sveikatos Mokslų Universitetas, Kaunas, Kaunas, Lithuania; [Schmitz] Bernd Ludwig, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg; [Mifsud] Stephanie, Mater Dei Hospital, Valletta, VLT, Malta; [Aehling] Carolin J., Amsterdam UMC - University of Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Allison] Celia E., Amsterdam UMC - University of Amsterdam, Amsterdam, Noord-Holland, Netherlands; [de Boer] Rients, Amsterdam UMC - University of Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Emal] Dina, Amsterdam UMC - University of Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Stevens] Markus Florian, Amsterdam UMC - University of Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Buitenhuis] Marielle, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [de Liefde] Inge I., Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [MacHotta] Andreas, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Scoones] Gail P., Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Staals] Lonneke M., Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Tomas] Jeremy J.P., Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [van der] Anouk, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Dortmont] Knijff Van, Erasmus MC Sophia Children’s Hospital, Rotterdam, Zuid-Holland, Netherlands; [Veldhuizen] Marianne, Haga Teaching Hospital, Leiden, Netherlands; [Alders] David J.C., Leids Universitair Medisch Centrum, Leiden, Zuid-Holland, Netherlands; [Bühre] Wolfgang F.F.A., Maastricht Universitair Medisch Centrum+, Maastricht, Limburg, Netherlands; [Schafrat] Eva, Maastricht Universitair Medisch Centrum+, Maastricht, Limburg, Netherlands; [Schreiber] Jan Uwe, Maastricht Universitair Medisch Centrum+, Maastricht, Limburg, Netherlands; [Vermeulen] Petronella Mari, Maastricht Universitair Medisch Centrum+, Maastricht, Limburg, Netherlands; [Hendriks] Mark P., Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Lako] Sandra J., Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Voet-Lindner] Marieke, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Pieters] Barbe M.A., Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Scheffer] Gert Jan S., Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Tielens] Luc K.P., Radboud University Medical Center, Nijmegen, Gelderland, Netherlands; [Absalom] Anthony Ray A., Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [Bergsma] Margot, Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [de Ruiter] Joke, Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [Meier] Sascha, Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [Volkers] Martin J., Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [Zweers] Tjerk, Universitair Medisch Centrum Groningen, Groningen, Groningen, Netherlands; [Beukers] Anne Maria, Amsterdam UMC - Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Boer] Christa, Amsterdam UMC - Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Dertinger] Jürgen A., Amsterdam UMC - Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, Netherlands; [Numan] Sandra C., University Medical Center Utrecht, Utrecht, Netherlands; [van Zaane] Bas, University Medical Center Utrecht, Utrecht, Netherlands; [Boerke] Wenche B., Rikshospitalet-Radiumhospitalet HF, Oslo, Oslo, Norway; [Ekiz] Nil, Rikshospitalet-Radiumhospitalet HF, Oslo, Oslo, Norway; [Stensrud] Kristoffer, Rikshospitalet-Radiumhospitalet HF, Oslo, Oslo, Norway; [Drage] Inger Marie, Ulleval University Hospital, Oslo, Oslo, Norway; [Isern] Erik Ramon, Universitetssykehuset i Trondheim, Trondheim, Trondelag, Norway; [Bartkowska-Sńiatkowska] Alicja, Department of Pediatric Anesthesiology and Intensive Care, Poznan University of Medical Sciences, Poznan, Wielkopolska Province, Poland; [Grześkowiak] Małgorzata, Department of Pediatric Anesthesiology and Intensive Care, Poznan University of Medical Sciences, Poznan, Wielkopolska Province, Poland; [Juzwa-Sobieraj] Magdalena, Department of Pediatric Anesthesiology and Intensive Care, Poznan University of Medical Sciences, Poznan, Wielkopolska Province, Poland; [Rosada-Kurasińska] Jowita, Department of Pediatric Anesthesiology and Intensive Care, Poznan University of Medical Sciences, Poznan, Wielkopolska Province, Poland; [Baranowski] Artur, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Jakubowska] Karina, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Lewandowska] Dorota, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Mierzewska-Schmidt] Magdalena, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Sawicki] Piotr, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Urban-Lechowicz] Magdalena, Public Paediatric Teaching Hospital, Medical University of Warsaw, Warsaw, MA, Poland; [Przemyslaw] Pomianek, Wroclaw Medical University, Wroclaw, DS, Poland; [Leal] Teresa Cristina Dos Santos, Centro Hospitalar Universitário de Santo António, Porto, Porto, Portugal; [Soares] Maria Da Conceição, Centro Hospitalar Universitário de Santo António, Porto, Porto, Portugal; [Pina] Pedro, Centro Hospitalar Universitário de Santo António, Porto, Porto, Portugal; [Pinho] Sílvia, Centro Hospitalar Universitário de Santo António, Porto, Porto, Portugal; [Patuleia] Maria Domingas, Santa Maria Hospital, Lisbon, Lisbon, Portugal; [Esteves] Catarina Cruz, Central Lisbon University Hospital Center, EPE (CHULC), Lisbon, Lisboa, Portugal; [Salgado] Helena, Hospital de Braga, Braga, Braga, Portugal; [Santos] Maria João Falle Gomes Dos, Hospital de Braga, Braga, Braga, Portugal; [Badeti] Rodica, Children Hospital 'Louis Turcanu", Romania; [Cîndea] Iulia, Emergency Clinical County Hospital Constanta, Constanta, Romania; [Oana] Loredana, Emergency Hospital for Children Cluj Napoca, Cluj Napoca, Romania; [Gurita] Adriana, Spitalul de copii “Maria Curie”, Romania; [Ilie] Luminita, Spitalul de copii “Maria Curie”, Romania; [Mocioiu] Gabriel, Spitalul de copii “Maria Curie”, Romania; [Tabăcaru] Radu, Spitalul de copii “Maria Curie”, Romania; [Trante] Irina, Spitalul de copii “Maria Curie”, Romania; [Munteanu] Valentin, St. Maria" Children' s Hospital-Iasi", Romania; [Morariu] Mihai, Mures County Clinical Emergency Hospital, Targu Mures, Romania; [Nyíri] Emese, Mures County Clinical Emergency Hospital, Targu Mures, Romania; [Budić] Ivana Z., Clinic for Anesthesiology and Intensive Care, University of Nis Medical Faculty, Nis, Serbia; [Marjanović] Vesna G., Clinic for Anesthesiology and Intensive Care, University of Nis Medical Faculty, Nis, Serbia; [Drašković] Biljana G., Children and Youth Health Care Institute of Vojvodina, Serbia; [Pandurov-Brlić] Marina, Children and Youth Health Care Institute of Vojvodina, Serbia; [Ilic] Jordanka, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Mandraš] Ana Dragoljub, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Rados] Zdenka, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Stanković] Nikola, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Suica] Maja, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Vasiljević] Sladjana, Mother and Child Health Care Institute of Serbia, Belgrade, Serbia; [Knezevic] Mirjana, University Children's Hospital, Belgrade, Belgrade, Serbia; [Milojević] Irina, University Children's Hospital, Belgrade, Belgrade, Serbia; [Petrov] Ivana, University Children's Hospital, Belgrade, Belgrade, Serbia; [Racic] Selena Puric, University Children's Hospital, Belgrade, Belgrade, Serbia; [Simić] Irena R., University Children's Hospital, Belgrade, Belgrade, Serbia; [Stevic] Marija M., University Children's Hospital, Belgrade, Belgrade, Serbia; [Vuličević] Irena, University Children's Hospital, Belgrade, Belgrade, Serbia; [Cabanová] Barbora, University Children's Hospital, Banska Bystrica, Banska Bystrica, Slovakia; [Hanula] Miloslav, University Children's Hospital, Banska Bystrica, Banska Bystrica, Slovakia; [Berger] Jelena, Univerzitetni Klinični Center Ljubljana, Ljubljana, Slovenia; [Janjatovic] Darja, Univerzitetni Klinični Center Ljubljana, Ljubljana, Slovenia; [Štupnik] Špela Pirtovšek, Univerzitetni Klinični Center Ljubljana, Ljubljana, Slovenia; [Kohn] Ivan, Karolinska Universitetssjukhuset, Stockholm, Stockholms, Sweden; [Lindestam] Ulf, Karolinska Universitetssjukhuset, Stockholm, Stockholms, Sweden; [Reinhard] Jarl, Karolinska Universitetssjukhuset, Stockholm, Stockholms, Sweden; [Castellheim] Albert Gyllencreutz, Drottning Silvias Barnsjukhus, Gothenburg, Vastra Gotaland, Sweden; [Sandström] Kerstin, Drottning Silvias Barnsjukhus, Gothenburg, Vastra Gotaland, Sweden; [Bengt] Sporre, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Dörenberg] Rainer, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Frykholm] Peter, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Garcia] Maria, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Kvarnström] Ann, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Pontén] Emma, Akademiska Sjukhuset, Uppsala, Uppsala, Sweden; [Bruelisauer] Thomas, University Hospital Bern, Bern, BE, Switzerland; [Erdoes] Gabor, University Hospital Bern, Bern, BE, Switzerland; [Kaiser] Heiko A., University Hospital Bern, Bern, BE, Switzerland; [Marchon] Mathias, University Hospital Bern, Bern, BE, Switzerland; [Riva] Thomas, University Hospital Bern, Bern, BE, Switzerland; [Seiler] Stefan, University Hospital Bern, Bern, BE, Switzerland; [Bögli] Yann, Centre Hospitalier Universitaire Vaudois, Lausanne, VD, Switzerland; [Dolci] Mirko, Centre Hospitalier Universitaire Vaudois, Lausanne, VD, Switzerland; [Marcucci] Carlos E., Centre Hospitalier Universitaire Vaudois, Lausanne, VD, Switzerland; [Pichon] Isabelle, Geneva Children's Hospital, Geneva, GE, Switzerland; [Casutt] Mattias, Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Hölzle] Martin, Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Hurni] Thomas, Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Jöhr] Martin, Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Anna-Ursina] null, Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Malar] null,; [Mauch] Jacqueline Y., Kantonsspital Luzern, Luzern, Lucerne, Switzerland; [Erb] Thomas O., Universitäts-Kinderspital Beider Basel, Basel, BS, Switzerland; [Oeinck] Karin, Universitäts-Kinderspital Beider Basel, Basel, BS, Switzerland; [Akin] Mine, Children's Health and Diseases Training and Research Hospital, Ankara, Ankara, Turkey; [Keskin] Gülsen, Children's Health and Diseases Training and Research Hospital, Ankara, Ankara, Turkey; [Şenayli] Yeşim Andiran, Children's Health and Diseases Training and Research Hospital, Ankara, Ankara, Turkey; [Kaya] Güner B., İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, Istanbul, Turkey; [Kendigelen] Pınar, İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, Istanbul, Turkey; [Tütüncü] Ayşe Çiǧdem, İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, Istanbul, Turkey; [Hatipoǧlu] Zehra, Çukurova Üniversitesi, Adana, Adana, Turkey; [Özcengiz] Dilek Dai, Çukurova Üniversitesi, Adana, Adana, Turkey; [Aksu] Hale, Dokuz Eylül Üniversitesi, Izmir, Turkey; [Öçmen] Elvan, Dokuz Eylül Üniversitesi, Izmir, Turkey; [Olguner] Çimen Gülben, Dokuz Eylül Üniversitesi, Izmir, Turkey; [Ayanoǧlu] Hilmi Ömer, Marmara Üniversitesi, Istanbul, Turkey; [Çorman Dinçer] Pelin, Marmara Üniversitesi, Istanbul, Turkey; [Umuroǧlu] Tümay, Marmara Üniversitesi, Istanbul, Turkey; [Azizoǧlu] Mustafa, Mersin Üniversitesi, Mersin, Turkey; [Birbiçer] H | en_US |
| dc.description.abstract | Background: Neonates and infants requiring anaesthesia are at risk of physiological instability and complications, but triggers for peri-anaesthetic interventions and associations with subsequent outcome are unknown. Methods: This prospective, observational study recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. The primary aim was to identify thresholds of pre-determined physiological variables that triggered a medical intervention. The secondary aims were to evaluate morbidities, mortality at 30 and 90 days, or both, and associations with critical events. Results: Infants (n=5609) born at mean (standard deviation [SD]) 36.2 (4.4) weeks postmenstrual age (35.7% preterm) underwent 6542 procedures within 63 (48) days of birth. Critical event(s) requiring intervention occurred in 35.2% of cases, mainly hypotension (>30% decrease in blood pressure) or reduced oxygenation (SpO<inf>2</inf> <85%). Postmenstrual age influenced the incidence and thresholds for intervention. Risk of critical events was increased by prior neonatal medical conditions, congenital anomalies, or both (relative risk [RR]=1.16; 95% confidence interval [CI], 1.04–1.28) and in those requiring preoperative intensive support (RR=1.27; 95% CI, 1.15–1.41). Additional complications occurred in 16.3% of patients by 30 days, and overall 90-day mortality was 3.2% (95% CI, 2.7–3.7%). Co-occurrence of intraoperative hypotension, hypoxaemia, and anaemia was associated with increased risk of morbidity (RR=3.56; 95% CI, 1.64–7.71) and mortality (RR=19.80; 95% CI, 5.87–66.7). Conclusions: Variability in physiological thresholds that triggered an intervention, and the impact of poor tissue oxygenation on patient's outcome, highlight the need for more standardised perioperative management guidelines for neonates and infants. Clinical trial registration: NCT02350348. © 2021 The Authors | en_US |
| dc.identifier.doi | 10.1016/j.bja.2021.02.016 | |
| dc.identifier.endpage | 1172 | en_US |
| dc.identifier.issn | 0007-0912 | |
| dc.identifier.issn | 1471-6771 | |
| dc.identifier.issue | 6 | en_US |
| dc.identifier.pmid | 33812668 | |
| dc.identifier.scopus | 2-s2.0-85106554104 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | 1157 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.bja.2021.02.016 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12712/36509 | |
| dc.identifier.volume | 126 | en_US |
| dc.identifier.wosquality | Q1 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier Ltd | en_US |
| dc.relation.ispartof | British Journal of Anaesthesia | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Critical Events | en_US |
| dc.subject | Neonates | en_US |
| dc.subject | Outcome | en_US |
| dc.subject | Patient Safety | en_US |
| dc.subject | Quality | en_US |
| dc.title | Morbidity and Mortality After Anaesthesia in Early Life: Results of the European Prospective Multicentre Observational Study, Neonate and Children Audit of Anaesthesia Practice in Europe (NECTARINE) | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication |