Publication:
Swimming Exercise Decreases the Absence-Like Epileptic Activity in WAG/Rij Rats

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dc.authorscopusid36999907100
dc.authorscopusid6602693377
dc.authorscopusid7003281190
dc.contributor.authorAygün, H.
dc.contributor.authorAyyildiz, M.
dc.contributor.authorAǧar, E.
dc.date.accessioned2020-06-21T12:26:56Z
dc.date.available2020-06-21T12:26:56Z
dc.date.issued2019
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Aygün] Hatice, Department of Physiology, Tokat Gaziosmanpaşa Üniversitesi, Tokat, Turkey; [Ayyildiz] Mustafa, Department of Physiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Aǧar] Erdal, Department of Physiology, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractAim: The aim of the present study was to evaluate the effects of long (60 min/day), moderate (30 min/day) and short (15 min/day) term daily swimming exercise programs for 90 days on durations and the spike-wave discharges (SWDs) seen in the electrocorticographic (ECoG) recordings of WAG/Rij rats with absence epilepsy. Materials and methods: Thirty-five adult male rats were divided into 5 groups as; Group 1: Control, Group 2: Sham (daily exposed to shallow water), Group 3: 15 min/day swimming exercise, Group 4: 30 min/day swimming exercise, Group 5: 60 min/day swimming exercise. After 90 days of swimming exercise program; ECoG recordings were taken for 2 h. Total number and cumulative length of SWDs in the recordings were used for evaluation of the seizures. Results: Both of the SWD parameters were significantly decreased in all swimming exercise groups compared to control and sham groups. The moderate swimming group (30 min/day) was found the most effective exercise program considering both of the SWD parameters of absence epilepsy. Conclusion: The results of the present study provide electrophysiologic evidence for the role of swimming exercise on the modulation of genetic absence epilepsy seizures in WAG/Rij rats. © 2019en_US
dc.identifier.doi10.1016/j.bbr.2019.01.060
dc.identifier.endpage148en_US
dc.identifier.issn0166-4328
dc.identifier.issn1872-7549
dc.identifier.pmid30716342
dc.identifier.scopus2-s2.0-85061189001
dc.identifier.scopusqualityQ2
dc.identifier.startpage145en_US
dc.identifier.urihttps://doi.org/10.1016/j.bbr.2019.01.060
dc.identifier.volume363en_US
dc.identifier.wosWOS:000460822600018
dc.identifier.wosqualityQ2
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofBehavioural Brain Researchen_US
dc.relation.journalBehavioural Brain Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpilepsyen_US
dc.subjectSWDen_US
dc.subjectSwimming Exerciseen_US
dc.subjectWAG/Rijen_US
dc.titleSwimming Exercise Decreases the Absence-Like Epileptic Activity in WAG/Rij Ratsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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