Lack of Correlation Between Vitamin D and Alkaline Phosphatase Levels Among Saudi Population

Abstract

Objective: The present study evaluated the correlation between Vitamin D and Alkaline phosphatase levels among the Saudi population. Methods: Blood samples of patients with a complaint of pain in various body parts and other clinical symptoms of Vitamin D deficiency were tested for the levels of Vitamin D and ALP. The analyzes were carried out using SPSS version 20.0 software. Results: Vitamin D and ALP levels of 460 patients were analyzed. The mean levels of Vitamin-D and ALP were found to be 22.03 +/- 13.5 and 89.02 +/- 44.9. About 356 patients (77.4%) out of 460 had Vit-D deficiency, whereas 421 patients (91.5%) out of 460 had ALP at normal ranges. From the analysis based on the nationality, Saudi 223 patients out of 280 showed vitamin D deficiency and 257 patients out of 280 had normal ALP levels. No correlation between serum ALP and vitamin D levels was observed (r = 0.05, p = 0.2). Conclusion: serum alkaline phosphatase cannot be considered as a useful marker to represent the Vitamin D deficiency among the population.