Publication:
Synthesis, Crystal Structure and Antioxidant Potential of Di-(N-cinnamyl) Fluoxetine Chloride

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dc.authorscopusid57016567000
dc.authorscopusid8361848500
dc.authorscopusid55830730500
dc.authorscopusid34769679600
dc.authorscopusid36039473500
dc.contributor.authorKanwal, N.
dc.contributor.authorSahin, O.
dc.contributor.authorHusaain, E.A.
dc.contributor.authorKhan, I.
dc.contributor.authorBüyuk̈güngör, O.
dc.date.accessioned2020-06-21T14:06:40Z
dc.date.available2020-06-21T14:06:40Z
dc.date.issued2013
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Kanwal] Nosheen, Department of Chemistry, Lahore College for Women University, Lahore, Pakistan; [Sahin] Onur, Department of Physics, Ondokuz Mayis University Faculty of Science and Arts, Samsun, Turkey; [Husaain] Erum A., Department of Chemistry, Lahore College for Women University, Lahore, Pakistan; [Khan] Islamullah, Department of Chemistry, Government College University Lahore, Lahore, Punjab, Pakistan; [Büyuk̈güngör] Orhan, Department of Physics, Ondokuz Mayis University Faculty of Science and Arts, Samsun, Turkeyen_US
dc.description.abstractA new derivative of Fluoxetine, N,N-dicinnamyl-N-methyl-3-phenyl-3- [4-(trifluoromethyl) phenoxy]butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTIR spectroscopy analysis. The titled compound [C<inf>35</inf>H<inf>37</inf>ClF <inf>3</inf>NO<inf>2</inf>] crystallized in monoclinic, having unit cell parameters a = 19.155(14) A°, b = 9.193(5) A°, c = 18.596(13) A° and belongs to P21/c space group. The molecule shows disorder of F atoms and was modeled as two different orientations. The one-dimensional crystal packing features weak C-H•••π interactions showing the formation of a chain along [001], provides stability to the crystal lattice. Antioxidant potential of Di-(N-Cinnamyl) Fluoxetine Chloride hydrate has been described and was found higher than Fluoxetine and N-Benzyl Fluoxetine.en_US
dc.identifier.doi10.4067/S0717-97072013000100001
dc.identifier.endpage1512en_US
dc.identifier.issn0717-9324
dc.identifier.issn0717-9707
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84882689232
dc.identifier.scopusqualityQ2
dc.identifier.startpage1508en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-97072013000100001
dc.identifier.urihttps://hdl.handle.net/20.500.12712/15986
dc.identifier.volume58en_US
dc.identifier.wosWOS:000331236900001
dc.identifier.wosqualityQ3
dc.language.isoenen_US
dc.publisherSociedad Chilena de Quimicaen_US
dc.relation.ispartofJournal of the Chilean Chemical Societyen_US
dc.relation.journalJournal of the Chilean Chemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidant Activityen_US
dc.subjectCrystal Structureen_US
dc.subjectDerivativeen_US
dc.subjectFluoxetineen_US
dc.titleSynthesis, Crystal Structure and Antioxidant Potential of Di-(N-cinnamyl) Fluoxetine Chlorideen_US
dc.typeArticleen_US
dspace.entity.typePublication

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