The Relationship Between Phase Angle Obtained From the Maximum Reactance and Fasting Glucose, Hemoglobin A1c in Type 2 Diabetes Mellitus

Abstract

Aim: The phase angle obtained from the maximum reactance (PA max) is a better potential indicator than the phase angles obtained from multiple frequencies. Our aim in this study is to investigate the correlation of PA max with fasting glucose and hemoglobin A1c in Type-2 Diabetes Mellitus (T2 DM). Material and Methods: The study was conducted prospectively, two groups were formed as T2 DM (n=75) and healthy controls (n=32) and their demographic variables were examined. Right hand, left hand, right leg, left leg, hand leg and leg leg segment measurements were taken with electrical impedance method and phase angle was obtained at maximum reactance. Correlations with fasting glucose, hemoglobin A1c and other variables were examined. Results: Fasting glucose, glycated hemoglobin A1c, age, body mass index, body fat percentage were found to be significantly higher in the T2 DM group compared with the healthy group. However, RH PA max, RL PA max, LL PA max, H_L PA max, and L_L PA max values were found to be significantly lower than in the healthy group. In T2 DM group, hemoglobin A1c was found significantly negative correlated with PA max in all segments, while fasting glucose is negatively correlated with all segments except LH Pamax. Conclusion: PA max is significantly reduced by the impaired glycemic index in T2 DM and is a potential marker reflecting metabolic status.