Intravenous Immunoglobulin Treatment and Evaluation of Autoinflammatory and Immunodeficiency-Associated Recurrent Parotitis Cases in Children

Abstract

Recurrent juvenile parotitis is a rare inflammatory condition characterized by recurrent, non-obstructive, and non-suppurative inflammation of the parotid gland during childhood. Diagnosis of the disease is based on clinical symptoms and laboratory tests. Although cases of recurrent parotitis are rare, various diseases can contribute to its etiology. Case series in the literature have reported diagnoses of immunodeficiency and autoimmune diseases. This study presents five cases diagnosed with autoimmune disease and immunodeficiency, successfully treated with intravenous immunoglobulin. © 2025 Ondokuz Mayis Universitesi. All rights reserved.