Publication:
Response to Hepatitis B Vaccine in HBsAg/Anti-HBs Negative and Anti-HBc Positive Subjects

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dc.authorscopusid7004406526
dc.authorscopusid24073322700
dc.authorscopusid36886143600
dc.authorscopusid7003851303
dc.authorscopusid26025098600
dc.contributor.authorSünbül, M.
dc.contributor.authorLeblebicioglu, H.
dc.contributor.authorEsen, S.
dc.contributor.authorEroǧlu, C.
dc.contributor.authorBarut, Ş.
dc.date.accessioned2020-06-21T15:50:10Z
dc.date.available2020-06-21T15:50:10Z
dc.date.issued2000
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Sünbül] Mustafa, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Leblebicioglu] Hakan, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Esen] Şaban, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Eroǧlu] Cafer, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Barut] Şener, Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis Üniversitesi, Samsun, Turkeyen_US
dc.description.abstractSome anti-HBc positive subjects have been encountered in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs). The aim of this study was to evaluate the response to hepatitis B vaccination in such cases. A total of 33 subjects who were HBsAg and anti-HBs negative, anti-HBc positive, with normal serum aminotransferase levels were included in the study. A recombinant hepatitis B vaccine was administered to subjects. Sera samples were obtained 1 month after each vaccination and tested for anti-HBs. HBV DNA and HBeAg were not detected in any subject. Anti-HBs levels were measured above 10≥ mIU/ml in 48.4% of cases after the first vaccination, 63.6% after the second vaccination and 90.9% after the third vaccination. Only 3 subjects (9.1%) lacked antibody response in spite of the 3-dose vaccination. In conclusion, preventive antibody levels were obtained after HBV vaccination in most of the HBsAg, anti-HBs negative, anti-HBc positive persons.en_US
dc.identifier.doi10.1080/00365540050165983
dc.identifier.endpage316en_US
dc.identifier.issn0036-5548
dc.identifier.issn1651-1980
dc.identifier.issue3en_US
dc.identifier.pmid10879605
dc.identifier.scopus2-s2.0-0033853949
dc.identifier.startpage315en_US
dc.identifier.urihttps://doi.org/10.1080/00365540050165983
dc.identifier.urihttps://hdl.handle.net/20.500.12712/22369
dc.identifier.volume32en_US
dc.identifier.wosWOS:000087696100016
dc.language.isoenen_US
dc.publisherTaylor and Francis A.S.en_US
dc.relation.ispartofScandinavian Journal of Infectious Diseasesen_US
dc.relation.journalScandinavian Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleResponse to Hepatitis B Vaccine in HBsAg/Anti-HBs Negative and Anti-HBc Positive Subjectsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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