Publication:
Saliva/Serum Ghrelin, Obestatin & Homocysteine Levels in Patients With Ischaemic Heart Disease

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dc.authorscopusid7005266578
dc.authorscopusid7003435455
dc.authorscopusid7005387041
dc.authorscopusid8523139900
dc.authorscopusid12752758300
dc.authorscopusid25630137900
dc.authorscopusid6506119378
dc.contributor.authorKiliç, N.
dc.contributor.authorDağlı, N.
dc.contributor.authorAydin, S.
dc.contributor.authorErman, F.
dc.contributor.authorBek, Y.
dc.contributor.authorAkin, O.
dc.contributor.authorKiliç, S.S.
dc.date.accessioned2020-06-21T13:19:53Z
dc.date.available2020-06-21T13:19:53Z
dc.date.issued2017
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Kiliç] Nermin, Department of Medical Biochemistry, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Dağlı] Necati, Department of Cardiology, Firat Üniversitesi, Elazig, Turkey; [Aydin] Süleyman, Department of Medical Biochemistry, Firat Üniversitesi, Elazig, Turkey; [Erman] Fazilet, Department of Medical Biochemistry, Firat Üniversitesi, Elazig, Turkey; [Bek] Yüksel, Department of Biostatistics, Ondokuz Mayis Üniversitesi, Samsun, Turkey; [Akin] Kadir Okhan, Laboratory of Biochemistry, Kecioren Education and Research Hospital, Ankara, Ankara, Turkey; [Kiliç] Süleyman Sirri, Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, Samsun, Turkey; [Erdemli] Haci Kemal, Department of Medical Biochemistry, Corum Training and Research Hospital, Corum, Corum, Turkey; [Alaçam] Hasan, Department of Medical Biochemistry, Hacettepe Üniversitesi, Ankara, Turkeyen_US
dc.description.abstractBackground: We aimed to compare ghrelin, obestatin, homocysteine (Hcy), vitamin B12 and folate levels in the serum and saliva of ischaemic heart disease patients. Methods: Serum and saliva were collected from 33 ischaemic heart disease (IHD) patients and 28 age-And body mass index-matched healthy individuals. Levels of acylated and desacylated ghrelin, obestatin and Hcy were determined using the ELISA method. Results: Acylated ghrelin, desacylated ghrelin and obestatin levels in the saliva were found to be higher than those in the serum of the control group, while acylated and desacylated ghrelin levels in the saliva were significantly lower than those in the serum. Obestatin levels were higher in IHD patients (p = 0.001). Saliva and serum vitamin B12 and folate levels in IHD patients were significantly lower than in the control group (p = 0.001). Conclusions: It was determined that serum ghrelin levels increased in ischaemic heart disease patients, while serum levels of obestatin decreased.en_US
dc.identifier.doi10.5830/CVJA-2016-075
dc.identifier.endpage164en_US
dc.identifier.issn1995-1892
dc.identifier.issn1996-3467
dc.identifier.issue3en_US
dc.identifier.pmid28759087
dc.identifier.scopus2-s2.0-85022101543
dc.identifier.scopusqualityQ3
dc.identifier.startpage159en_US
dc.identifier.urihttps://doi.org/10.5830/CVJA-2016-075
dc.identifier.volume28en_US
dc.identifier.wosWOS:000405948700007
dc.identifier.wosqualityQ4
dc.language.isoenen_US
dc.publisherClinics Cardive Publishing (PTY)Ltd PO Box 1013, Durbanville, 7551en_US
dc.relation.ispartofCardiovascular Journal of Africaen_US
dc.relation.journalCardiovascular Journal of Africaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGhrelinen_US
dc.subjectHomocysteineen_US
dc.subjectIschaemiaen_US
dc.subjectObestatinen_US
dc.subjectSalivaen_US
dc.titleSaliva/Serum Ghrelin, Obestatin & Homocysteine Levels in Patients With Ischaemic Heart Diseaseen_US
dc.typeArticleen_US
dspace.entity.typePublication

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