Relationship between neutrophil-to-lymphocyte ratio, d-dimer and troponin-I values and pulmonary embolism severity index
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Aim: We aimed to determine whether Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), Platelet-to-Lymphocyte Ratio (PLR), D-dimer, and troponin values were correlated with the simplified Pulmonary Embolism Severity Index (sPESI) in patients diagnosed as having Pulmonary Embolism (PE) in the emergency room.Material and Methods: Forty-three patients diagnosed as having PE in the emergency department were divided into low and high-risk groups according to the sPESI. We investigated whether NLR, MLR, and PLR, d-dimer, troponin-I, and Pulmonary Artery Pressure (PAP) had any effect in determining the severity of PE. Also, patients were divided into groups as those with PAP 20 or 20 mm Hg, Systolic Blood Pressure (SBP) 100 or 100 mm Hg, and those receiving or not receiving thrombolytic treatment, and compared.Results: There was a statistically significant difference between patients with low sPESI (n10) and those with high sPESI (n33) in terms of age (p0.001), pulse (p0.016), oxygen saturation (p0.039), troponin-I (p0.029) and PAP (p0.032), but there was no difference between the groups in terms of NLR (p0.796), MLR (p0.656), PLR (p0.863), and d-dimer (p0.343). There was a statistically significant difference between patients who did (n6) and did not (n37) receive thrombolytic treatment in terms of troponin-I (p0.012), but there was no difference between the groups in terms of NLR (p0.861), MLR (p0.335), and PLR (p0.277).Conclusion: NLR, MLR, PLR and d-dimer levels were found not to be effective in determining the severity of PE. Troponin-I was associated with sPESI and was considered as an effective marker in determining the thrombolytic treatment.
SourceAnnals of Medical Research
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