| dc.contributor.author | Kanwal, Nosheen | |
| dc.contributor.author | Sahin, Onur | |
| dc.contributor.author | Husaain, Erum A. | |
| dc.contributor.author | Khan, Islam Ullah | |
| dc.contributor.author | Büyükgüngör, Orhan | |
| dc.date.accessioned | 2020-06-21T14:06:40Z | |
| dc.date.available | 2020-06-21T14:06:40Z | |
| dc.date.issued | 2013 | |
| dc.identifier.issn | 0717-9707 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12712/15986 | |
| dc.description | Sahin, Onur/0000-0003-3765-3235 | en_US |
| dc.description | WOS: 000331236900001 | en_US |
| dc.description.abstract | A new derivative of Fluoxetine, N,N-dicinnamyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl) phenoxy] butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTIR spectroscopy analysis. The titled compound [C35H37ClF3NO2] crystallized in monoclinic, having unit cell parameters a = 19.155(14) A degrees, b = 9.193(5) A degrees, c = 18.596(13) A degrees and belongs to P2(1)/c space group. The molecule shows disorder of F atoms and was modeled as two different orientations. The one-dimensional crystal packing features weak C-H center dot center dot center dot pi interactions showing the formation of a chain along [001], provides stability to the crystal lattice. Antioxidant potential of Di-(N-Cinnamyl) Fluoxetine Chloride hydrate has been described and was found higher than Fluoxetine and N-Benzyl Fluoxetine. | en_US |
| dc.description.sponsorship | Higher Education Commission, Islamabad, PakistanHigher Education Commission of Pakistan | en_US |
| dc.description.sponsorship | Authors acknowledge the financial support from Higher Education Commission, Islamabad, Pakistan, under its Indigenous PhD Program batch (III). Authors also thank Mr. Shahzad Sharif, Dr. Maqsood Ahmed, Ms. Sidra Farid and Ms. Jeveria Rehman for their assistance and helpful discussions. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Soc Chilena Quimica | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Fluoxetine | en_US |
| dc.subject | Derivative | en_US |
| dc.subject | Crystal structure | en_US |
| dc.subject | Antioxidant activity | en_US |
| dc.title | Synthesis, Crystal Structure and Antioxidant Potential of Di-(N-Cinnamyl) Fluoxetine Chloride | en_US |
| dc.type | article | en_US |
| dc.contributor.department | OMÜ | en_US |
| dc.identifier.volume | 58 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 1508 | en_US |
| dc.identifier.endpage | 1512 | en_US |
| dc.relation.journal | Journal of the Chilean Chemical Society | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
