Hyaluronidase in ophthalmic evisceration surgery

Abstract

Background To research the effectiveness of hyaluronidase in evisceration surgery. Methods A total of 34 patients were studied as three groups: conventional surgery group (n=13); isotonic fluid group (n=8); and hyaluronidase group (n=13). Hyaluronidase and isotonic fluid were introduced into the uveo-scleral space. Intraocular content was removed, if possible by aone-scoopmethod, with the aid of a spoon. Results Removing all the intraocular contentas a one-scoop methodwas achieved in 10 of 13 (77%) in the hyaluronidase group and four of eight (50%) in the isotonic fluid group.The one-scoop method was not possible in any case without the introduction of fluid.The mean durations for the evisceration procedure were 32, 36.6 and 40.5min in the three groups, respectively (P<0.05). Conclusions Using hyaluronidase in evisceration surgery greatly facilitates and speeds up the removal of all the intraocular content in ophthalmic evisceration surgery.