Radiological and Clinical Manifestations of Metastatic Pulmonary Calcification in a Patient with Parathyroid Hyperplasia

Abstract

Metastatic pulmonary calcification (MPC) is the deposition of calcium salts in the walls of the alveoli and small blood vessels in normal tissue. MPC may be associated with end-stage renal disease, primary and secondary hyperparathyroidism, diffuse skeletal malignancy, intravenous calcium therapy, massive osteolysis from metastases, and multiple myeloma. We present a case of a 53-year-old-man with end-stage renal disease and primary hyperparathyroidism presented with hip and chest pain. Computed tomography of the chest revealed multiple, ground-glass opacities associated with poorly defined centrilobular nodules and numerous calcific nodules, consistent with MPC.