Browsing by Author "Dege N."
Now showing items 1-20 of 24
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1,4-disubstituted 1h-1,2,3-triazoles for renal diseases: Studies of viability, anti-inflammatory, and antioxidant activities
Cheng C.-Y.; Haque A.; Hsieh M.-F.; Hassan S.I.; Faizi M.S.H.; Dege N.; Khan M.S. (MDPI AG, 2020)Inflammation is a hallmark of many metabolic diseases. We previously showed that ferrocene-appended 1H-1,2,3-triazole hybrids inhibit nitric oxide (NO) production in in vitro models of lipopolysaccharide-induced inflammation ... -
1-(Adamantan-1-yl)-3-(4-fluorophenyl)thiourea
In the title molecule, C17H21FN2S, the mean planes of the benzene ring and the thiourea fragment form a dihedral angle of 61.93 (9)°. In the crystal, pairs of weak N - H?S inter-actions link the molecules, forming inversion ... -
1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]-methyl}quinazoline-2,4(1H,3H)-dione
In the title molecule, C18H16N2O 3, the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the ... -
2-[(2-methoxyethyl)sulfanyl]-4-(2-methylpropyl)-6-oxo-1, 6-dihydro-pyrimidine-5-carbonitrile
El-Emam A.A.; Demirta G.; Dege N.; Al-Deeb O.A.; El-Brollosy N.R. (2012)In the title compound, C12H17N3O 2S, the 4-methyl-2-methyl-sulfanyl-6-oxo-1,6-dihydro-pyrimidine-5- carbonitrile part of the molecule is almost planar (r.m.s deviation = 0.062 Å). In the crystal, molecules form centrosymmetric ... -
2-{(E)-[(2-Methyl-3-nitrophenyl)imino]methyl}-4-nitrophenol
Tanak H.; Toğurman F.; Kalecik S.; Dege N.; Yavuz M. (2013)The title compound, C14H11N3O5, is a Schiff base that adopts the enol-imine tautomeric form in the solid state. The dihedral angle between the aromatic rings is 37.4 (3)° and the dihedral angles between the nitro groups ... -
Crystal structural and in silico studies of Schiff bases derived from 4-aminoantipyrine
Ossai V.; Obiefuna A.P.; Laraps B.C.; Okenyeka O.U.; Ezeorah J.C.; Dege N.; Obasi N.L. (Elsevier Masson SAS, 2020)Two Schiff bases, 4-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-1,5,-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (APNA) and 4-[(2,3-Dihydroxybenzylidene)amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (SBAP) ... -
Crystal structure and Hirshfeld surface analysis of (E)-6-(4-hydroxy-3-methoxystyryl)-4,5-dihydropyridazin-3(2H)-one
Daoui S.; Baydere C.; Kalai F.E.; Saddik R.; Dege N.; Karrouchi K.; Benchat N. (International Union of Crystallography, 2019)In the title compound, C13H14N2O3, the dihydropyridazine ring (r.m.s. deviation = 0.166 Å) has a screw-boat conformation. The dihedral angle between its mean plane and the benzene ring is 0.77 (12)°. In the crystal, ... -
(E)-N-(1-Benzothiophen-3-ylmethylidene)-2,6-dimethylaniline
Kahveci Yağci N.; Dege N.; Gümüş S.; Ağar E.; Soylu M.S. (2012)In the title compound, C 17H 15NS, the benzothio-phene residue and the substituted benzene ring are oriented at a dihedral angle of 61.99 (7)°. An intermolecular C - H?? interaction contributes to the stability of the ... -
Experimental and theoretical (DFT) studies of poly[octa-?3-acesulfamato-o, o:n, o';o',n:o, o-tetraaquatetrabarium(II)] and poly[octa-?3-acesulfamato-o, o:n, o';o', n:o, o-tetraaquatetrastrontium(II)] complexes
Içbudak H.; Demirtaş G.; Dege N. (Macedonian Journal of Chemistry and Chemical Engineering, 2015)Two new one-dimensional coordination polymers of barium(II) and strontium(II)-acesulfamato complexes such as [Ba(C4H4NO4S)2(H2O)]n (1) and [Sr(C4H4NO4S)2(H2O)]n (2) have been synthesized and their molecular structures were ... -
Experimental and theoretical studies of bis[(E)-1-((3-chloro-4-methylphenylimino)methyl)naphthalen-2-olate-N,O]copper(II)
A novel Schiff base copper complex, bis[(E)-1-((3-chloro-4-methylphenylimino)methyl) naphthalen-2-olate-N,O]copper(II), has been synthesized and characterized by FT-IR and X-ray diffraction techniques. The compound ... -
Novel metal complexes containing 6-methylpyridine-2-carboxylic acid as potent ?-glucosidase inhibitor: synthesis, crystal structures, DFT calculations, and molecular docking
Abstract: The World Health Organization (WHO) report shows that diabetes mellitus (DM) will be one of the ten deadly diseases in the near future. The best way to prevent DM is to decrease blood glucose levels and keep under ... -
Synthesis and Crystal Structure of Nickel(II) and Zinc(II) Complexes with O-Propylxanthate and N, N, N?,N?-Tetramethylethylenediamine
Qadir A.M.; Dege N. (Pleiades Publishing, 2019)The reaction of NiCl2·6H2O or Zn(CH3CO2)·2H2O with potassium O-propylxanthate (KS2COC3H7) and N, N, N?,N?-tetramethylethylenediamine (tmeda) affords monomeric complexes of the formula [M(S2COC3H7)2(tmeda)] (M = Ni(II) 1; ... -
Synthesis and X-ray crystal structures of two different zinc (II) complexes of N,N?-cyclohexane-1,2-diylidene-bis(4-fluorobenzoylhydrazide) based on zinc salt effect
Bariz OmarAli A.-A.; Jasim M. Al-Karawi A.; Dege N.; Kansız S.; Abdulkareem D. Ithawi H. (Elsevier B.V., 2020)Reaction of zinc chloride or zinc nitrate hexahydrate with N,N?-cyclohexane-1,2-diylidene-bis(4-fluorobenzoylhydrazide) (L) in acetonitrile and under ambient conditions, produced two different zinc(II) complexes 1 and 2 ... -
Synthesis of a novel benzimidazole moiety-appended schiff base derivative: Fluorescence and chemosensor study
Sen P.; Zeki Yildiz S.; Dege N.; Yasa Atmaca G.; Erdogmus A.; Dege M. (Turkish Chemical Society, 2018)In this study, we synthesized a novel benzimidazole-based Schiff base; (E)-4,4'-methylenebis(2-((E)-(((1H-benzo[d]imidazol-2-yl)methyl)imino)methyl)phenol) (3) was synthesized by the condensation of 5,5'-methylenebis(2-h ... -
Synthesis, characterization and crystal structure of a novel decavanadate salt, [V0.50(H2O)5]2[H2(V10O28)]·4(H2O)
A novel decavanadate salt, [V0.50(H2O)5]2[H2(V10O28)]·4(H2O), was obtained by the reaction of NH4VO3 with chinhydrone in an acidic medium. The title compound was characterized in the solid and solution phases by FT-IR, ... -
Synthesis, crystal structure, DFT calculations, Hirshfeld surface, vibrational and optical properties of a novel hybrid non-centrosymmetric material (C10H15N2)2H2P2O7
Oueslati Y.; Kansız S.; Valkonen A.; Sahbani T.; Dege N.; Smirani W. (Elsevier B.V., 2019)This present work undertakes the study of a novel organic–inorganic hybrid material, which has been obtained successfully by an acid-base reaction at room temperature and structurally studied by the single crystal X-ray ... -
Synthesis, crystal structure, Hirshfeld surface analysis, In-Silico assessment of druggability and molecular docking studies of Schiff base compound
Dege N.; Aydın A.S.; Ağar E.; Kansız S.; JoseKavitha S.; BalaSubramani K.; Rajakannan V. (Elsevier B.V., 2020)In this crystal structure (I), an intramolecular O—H···O hydrogen bond forms S(6) ring motif. Furthermore, this structure is stabilized by C—H···O hydrogen bonding interaction to form a chain along a-axis. The intermolecular ... -
Synthesis, crystal structure, Hirshfeld surface analysis, spectral characterization, and quantum computational evaluation of (E)-2-(((4-bromophenyl)imino)methyl)-6-methylphenol
A newly synthesized compound, (E)-2-(((4-bromophenyl)imino)methyl)-6-methylphenol (C14H12BrNO), is analyzed in detail for structural clarification by experimental X-ray, Fourier transform IR, 1H and 13C NMR, and UV–vis ... -
Synthesis, experimental and theoretical characterization of (E)-2-((2,3-dimethylphenyl)amino)-N’-(furan-2-ylmethylene)benzohydrazide
Albayati M.R.; Kansız S.; Lgaz H.; Kaya S.; Dege N.; Ali I.H.; Chung I.-M. (Elsevier B.V., 2020)Hydrazone derivatives have drawn much attention because of their large pharmacological applications. In the present work, the compound (E)-2-((2,3-dimethylphenyl)amino)-N’-(furan-2-ylmethylene)benzohydrazide, noted C20H19N3O2 ... -
Synthesis, molecular structure, hirshfeld surface analysis, spectroscopic and computational studies (DFT) of 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(methanylylidene))bis(2-(tert-butyl)-4-methylphenol)
Schiff bases have been used in biological processes and as chelating agents for several decades. In this work, a Schiff base compound was obtained with the condensation of o-phenylenediamine and an aromatic aldehyde. The ...
